Bus tickets Antofagasta to Santiago, RM from £18

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Which bus from Antofagasta to Santiago, RM is the best?

Check the bus schedule for Antofagasta to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Cikbus Elité, Pullman San Andres or Pluss Chile. To see the full timetable for all coaches just use or search and compare.

today
from £19
tomorrow
from £24
Wednesday
from £18
Thursday
from £18
Friday
from £21
Saturday
from £22
Sunday
from £18

Cheapest bus trips today

Prices are for one way and one person
  • Cikbus Elité
    18h 50m
    0
    01:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:50
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    £19
  • Turbus
    18h 15m
    0
    04:15
    Antofagasta
    Terminal Buses Camus
    22:30
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    £23
  • Nueva Andimar Vip
    19h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £24
  • Pluss Chile
    18h 20m
    0
    02:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £26
  • Pullman Bus
    18h 30m
    0
    00:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    Economy
    £27

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Nueva Andimar Vip
    19h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £24
  • Turbus
    17h 50m
    0
    00:20
    Antofagasta
    Terminal Buses Camus
    18:10
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    £24
  • Pullman Bus
    19h 0m
    0
    15:30
    Antofagasta
    Terminal Buses Camus
    10:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Cikbus Elité
    18h 50m
    0
    01:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:50
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £25
  • Pluss Chile
    18h 20m
    0
    02:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £26
  • Did you know that if you travel from Antofagasta to Santiago, RM via La Serena, you can save more than £3? You can find the corresponding connections below.
    • kupos.cl
      17h 10m
      0
      01:10
      Antofagasta
      Terminal Buses Camus
      12:30
      La Serena
      Bus Stop
      0
      kupos.cl
      Premium Economy
      £16
      • Waiting Time 0h 10m
    • kupos.cl
      5h 40m
      0
      12:40
      La Serena
      Bus Stop
      18:20
      Santiago, RM
      Terminal Alameda
      0
      kupos.cl
      Premium Economy
      £6
    Travel Time is 0h 40m shorter, and you will save £3

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Cikbus Elité
    18h 50m
    0
    01:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:50
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    £18
  • Pullman Bus
    18h 30m
    0
    00:30
    Antofagasta
    Terminal Buses Camus
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Nueva Andimar Vip
    19h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Premium Economy
    £25
  • Pluss Chile
    18h 20m
    0
    02:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £26
  • Pullman San Andres
    17h 30m
    0
    03:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £28

Cheapest bus trips Thursday

Prices are for one way and one person
  • Cikbus Elité
    18h 50m
    0
    01:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:50
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    £18
  • Nueva Andimar Vip
    19h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    22:35
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £24
  • Turbus
    18h 15m
    0
    04:15
    Antofagasta
    Terminal Buses Camus
    22:30
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    £24
  • Pullman Bus
    18h 30m
    0
    00:30
    Antofagasta
    Terminal Buses Camus
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Pullman San Andres
    17h 1m
    0
    23:59
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £26

Cheapest bus trips Friday

Prices are for one way and one person
  • Turbus
    18h 35m
    0
    03:25
    Antofagasta
    Terminal Buses Camus
    22:00
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    £21
  • Cikbus Elité
    18h 40m
    0
    01:10
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:50
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £23
  • Pullman Bus
    18h 30m
    0
    00:30
    Antofagasta
    Terminal Buses Camus
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Pluss Chile
    18h 20m
    0
    02:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £26
  • Cormar Bus
    18h 10m
    0
    21:30
    Antofagasta
    Terminal Buses Camus
    15:40
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £28

Cheapest bus trips Saturday

Prices are for one way and one person
  • Turbus
    18h 35m
    0
    03:25
    Antofagasta
    Terminal Buses Camus
    22:00
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    £22
  • Nueva Andimar Vip
    19h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    20:35
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £24
  • Pullman Bus
    18h 30m
    0
    00:30
    Antofagasta
    Terminal Buses Camus
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Cormar Bus
    18h 10m
    0
    21:30
    Antofagasta
    Terminal Buses Camus
    15:40
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £28
  • Pullman San Andres
    17h 0m
    0
    01:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    18:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £28

Cheapest bus trips Sunday

Prices are for one way and one person
  • Cikbus Elité
    17h 0m
    0
    06:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    23:00
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    £18
  • Nueva Andimar Vip
    19h 0m
    0
    21:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    16:30
    Santiago, RM
    Sur Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £24
  • Pullman Bus
    18h 30m
    0
    00:30
    Antofagasta
    Terminal Buses Camus
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Turbus
    17h 10m
    0
    01:10
    Antofagasta
    Terminal Buses Camus
    18:20
    Santiago, RM
    Terminal Alameda
    0
    Turbus
    Premium Economy
    £25
  • Pullman San Andres
    17h 1m
    0
    23:59
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £26

What is the best day and time to travel by bus between Antofagasta and Santiago, RM?

Here is the frequency of all coach connections from Antofagasta to Santiago, RM. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Thursday is the busiest day, with more than 153 daily coaches from Antofagasta to Santiago, RM. Saturday has instead the fewest connections, with only 47 daily coaches between Antofagasta and Santiago, RM.
The busiest time of the day is the Evening, with 341 coaches from Antofagasta to Santiago, RM, while Morning sees the fewest connections between Antofagasta and Santiago, RM, with 52 offers.

All facts for Antofagasta to Santiago, RM bus at a glance

Compare all coach operators like Cikbus Elité, Pullman San Andres and Pluss Chile that travel daily 113 times by bus from Antofagasta to Santiago, RM in one click. Book your Antofagasta to Santiago, RM bus ticket starting from £18!

Cheapest Bus £18
Fastest Bus 16h 55m
Earliest Coach 00:15
Latest Coach 23:59
Daily Bus Connections 113 Ø
Distance 1,089.2 km
Coach Companies Cikbus Elité, Pullman San Andres, Pluss Chile, Pullman Bus, Nueva Andimar Vip, Turbus and Cormar Bus

What are the cheapest coach tickets from Antofagasta to Santiago, RM?

Every day, 113 buses from 7 coach companies leave Antofagasta for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 28/04/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 28/04
£19
Tuesday 29/04
£17
Wednesday 30/04
£24
Thursday 01/05
£24
Friday 02/05
£17
Saturday 03/05
£22
Sunday 04/05
£17
Monday 05/05
£21
Tuesday 06/05
£21
Wednesday 07/05
£21
Thursday 08/05
£21
Friday 09/05
£21
Saturday 10/05
£17
Sunday 11/05
£21
Monday 12/05
£21
Tuesday 13/05
£21
Wednesday 14/05
£21
Thursday 15/05
£21
Friday 16/05
£21
Saturday 17/05
£33
Sunday 18/05
£21
Monday 19/05
£17
Tuesday 20/05
£26
Wednesday 21/05
£21
Thursday 22/05
£21
Friday 23/05
£33
Saturday 24/05
£21
Sunday 25/05

The cheapest time to travel from Antofagasta to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to Santiago, RM, for the next 30 days.
With a price starting from £18, Wednesday is the cheapest day for a coach from Antofagasta to Santiago, RM. Tuesday instead is the most expensive day with prices starting from £24.
Morning is the cheapest day time for bus tickets from Antofagasta to Santiago, RM, with £18. Afternoon is the most expensive time of the day with prices starting from £21.

How to save money travelling from Antofagasta to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to Santiago, RM are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Antofagasta and Santiago, RM

Here is a map with all coach stations in Antofagasta and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Antofagasta to Santiago, RM? Compare all modes of transports from Antofagasta to Santiago, RM.

All you need to know when you travel by bus from Antofagasta to Santiago, RM

Check all information on comfort and services on the coaches from Antofagasta to Santiago, RM. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Antofagasta to Santiago, RM bus

How much does a Antofagasta Santiago, RM coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Antofagasta Santiago, RM bus trip is available from £18 and takes 18h 50m. Compare offers and save money!

How much could I save by comparing buses from Antofagasta to Santiago, RM?

This connection is offered by 7 companies with ticket prices ranging from £18 to £54. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago, RM.

How many connections are available for the Antofagasta Santiago, RM route on average every day?

Each day, the bus route from Antofagasta to Santiago, RM is offered by roughly 113 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santiago, RM from Antofagasta take?

The quickest coach from Antofagasta to Santiago, RM is provided by Turbus and takes 16h 55m. Coach tickets for this connection cost £32. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Antofagasta to Santiago, RM?

The earliest bus to Santiago, RM departs from Antofagasta at 00:15. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Antofagasta to Santiago, RM?

The latest bus to Santiago, RM departs from Antofagasta at 23:59. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Antofagasta Santiago, RM route?

Passengers looking to travel from Antofagasta to Santiago, RM can travel with Cikbus Elité, Pullman San Andres and Pluss Chile. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Antofagasta and Santiago, RM?

You can check all the direct connections between Antofagasta and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Cikbus Elité, Pullman San Andres and Pluss Chile.

What can I take with me on the bus to Santiago, RM from Antofagasta?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Antofagasta Santiago, RM bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to Santiago, RM on your planned travel date.

Available seat classes which are offered on the bus route Antofagasta to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to Santiago, RM

Here’s an overview of the most popular bus routes to Antofagasta and to Santiago, RM. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Bus Arica, AP to Antofagasta Bus Arica, AP to Antofagasta
Bus Iquique to Antofagasta Bus Iquique to Antofagasta
Coach La Serena to Antofagasta Coach La Serena to Antofagasta
Coach from Cochabamba to Antofagasta Coach from Cochabamba to Antofagasta
Concepción to Santiago, RM coach Concepción to Santiago, RM coach
Copiapó to Santiago, RM coach Copiapó to Santiago, RM coach
Bus Villarrica (CL) to Santiago, RM Bus Villarrica (CL) to Santiago, RM
Coach from Chillán to Santiago, RM Coach from Chillán to Santiago, RM
Popular Airport Transfers to Antofagasta and to Santiago, RM
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