Bus tickets Madrid to Santander from £21

Find a coach from Madrid to Santander: Compare 2 companies
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Which bus from Madrid to Santander is the best?

Check the bus schedule for Madrid to Santander. Here is a selection of the cheapest coach trips for the next days from bus operators like ALSA or FlixBus. To see the full timetable for all coaches just use or search and compare.

today
from £33
tomorrow
from £34
Friday
from £34
Saturday
from £21
Sunday
from £33
Monday
from £33
Tuesday
from £21

Cheapest bus trips today

Prices are for one way and one person
  • ALSA
    5h 30m
    0
    15:30
    Madrid
    Avenida de América Coach Station
    21:00
    Santander
    Coach Station
    0
    ALSA
    Economy
    £33
  • ALSA
    5h 45m
    0
    16:30
    Madrid
    Avenida de América Coach Station
    22:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 30m
    0
    18:30
    Madrid
    Avenida de América Coach Station
    00:00
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • FlixBus
    16h 45m
    0
    16:40
    Madrid
    Sur Bus Station
    09:25
    Santander
    Coach Station
    0
    FlixBus
    Economy
    £95
  • Did you know that if you travel from Madrid to Santander via Valladolid, you can save more than £18? You can find the corresponding connections below.
    • Linecar
      4h 40m
      0
      09:35
      Madrid
      Poligono 17 Rustica
      09:40
      Valladolid
      Coach Station
      0
      Linecar
      Economy
      £1
      • Waiting Time 1h 20m
    • Busbud
      3h 15m
      0
      11:00
      Valladolid
      Coach Station
      14:15
      Santander
      Coach Station
      0
      Busbud
      Economy
      £14
    Travel Time is 0h 50m shorter, and you will save £18

Cheapest bus trips tomorrow

Prices are for one way and one person
  • ALSA
    5h 45m
    0
    16:30
    Madrid
    Avenida de América Coach Station
    22:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 30m
    0
    18:30
    Madrid
    Avenida de América Coach Station
    00:00
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 45m
    0
    19:00
    Madrid
    Avenida de América Coach Station
    00:45
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • FlixBus
    16h 45m
    0
    16:40
    Madrid
    Sur Bus Station
    09:25
    Santander
    Coach Station
    0
    FlixBus
    Economy
    £92
  • Did you know that if you travel from Madrid to Santander via Valladolid, you can save more than £19? You can find the corresponding connections below.
    • Linecar
      4h 40m
      0
      09:35
      Madrid
      Poligono 17 Rustica
      09:40
      Valladolid
      Coach Station
      0
      Linecar
      Economy
      £1
      • Waiting Time 1h 20m
    • Busbud
      3h 15m
      0
      11:00
      Valladolid
      Coach Station
      14:15
      Santander
      Coach Station
      0
      Busbud
      Economy
      £14
    Travel Time is 0h 50m shorter, and you will save £19

Cheapest bus trips Friday

Prices are for one way and one person
  • ALSA
    5h 45m
    0
    10:30
    Madrid
    Avenida de América Coach Station
    16:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 30m
    0
    13:00
    Madrid
    Avenida de América Coach Station
    18:30
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 45m
    0
    16:30
    Madrid
    Avenida de América Coach Station
    22:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 30m
    0
    18:30
    Madrid
    Avenida de América Coach Station
    00:00
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 50m
    0
    08:00
    Madrid
    Avenida de Aragon
    13:50
    Santander
    Coach Station
    0
    ALSA
    Economy
    £36
  • Did you know that if you travel from Madrid to Santander via Valladolid, you can save more than £19? You can find the corresponding connections below.
    • Linecar
      4h 40m
      0
      09:35
      Madrid
      Poligono 17 Rustica
      09:40
      Valladolid
      Coach Station
      0
      Linecar
      Economy
      £1
      • Waiting Time 1h 20m
    • Busbud
      3h 15m
      0
      11:00
      Valladolid
      Coach Station
      14:15
      Santander
      Coach Station
      0
      Busbud
      Economy
      £14
    Travel Time is 0h 50m shorter, and you will save £19

Cheapest bus trips Saturday

Prices are for one way and one person
  • ALSA
    5h 50m
    0
    08:00
    Madrid
    Avenida de Aragon
    13:50
    Santander
    Coach Station
    0
    ALSA
    Economy
    £21
  • ALSA
    5h 45m
    0
    10:30
    Madrid
    Avenida de Aragon
    16:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £21
  • ALSA
    5h 30m
    0
    13:00
    Madrid
    Avenida de América Coach Station
    18:30
    Santander
    Coach Station
    0
    ALSA
    Economy
    £21
  • FlixBus
    16h 45m
    0
    16:40
    Madrid
    Sur Bus Station
    09:25
    Santander
    Coach Station
    0
    FlixBus
    Economy
    £93
  • Did you know that if you travel from Madrid to Santander via Valladolid, you can save more than £6? You can find the corresponding connections below.
    • Linecar
      4h 40m
      0
      09:35
      Madrid
      Poligono 17 Rustica
      09:40
      Valladolid
      Coach Station
      0
      Linecar
      Economy
      £1
      • Waiting Time 1h 20m
    • Busbud
      3h 15m
      0
      11:00
      Valladolid
      Coach Station
      14:15
      Santander
      Coach Station
      0
      Busbud
      Economy
      £14
    Travel Time is 0h 50m shorter, and you will save £6

Cheapest bus trips Sunday

Prices are for one way and one person
  • ALSA
    5h 50m
    0
    08:00
    Madrid
    Avenida de América Coach Station
    13:50
    Santander
    Coach Station
    0
    ALSA
    Economy
    £33
  • ALSA
    5h 45m
    0
    10:30
    Madrid
    Avenida de América Coach Station
    16:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 45m
    0
    16:30
    Madrid
    Avenida de América Coach Station
    22:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • FlixBus
    16h 45m
    0
    16:40
    Madrid
    Sur Bus Station
    09:25
    Santander
    Coach Station
    0
    FlixBus
    Economy
    £94
  • Did you know that if you travel from Madrid to Santander via Valladolid, you can save more than £18? You can find the corresponding connections below.
    • Linecar
      4h 40m
      0
      09:35
      Madrid
      Poligono 17 Rustica
      09:40
      Valladolid
      Coach Station
      0
      Linecar
      Economy
      £1
      • Waiting Time 1h 20m
    • Busbud
      3h 15m
      0
      11:00
      Valladolid
      Coach Station
      14:15
      Santander
      Coach Station
      0
      Busbud
      Economy
      £14
    Travel Time is 1h 5m shorter, and you will save £18

Cheapest bus trips Monday

Prices are for one way and one person
  • ALSA
    5h 50m
    0
    08:00
    Madrid
    Avenida de América Coach Station
    13:50
    Santander
    Coach Station
    0
    ALSA
    Economy
    £33
  • ALSA
    5h 45m
    0
    10:30
    Madrid
    Avenida de América Coach Station
    16:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • ALSA
    5h 30m
    0
    13:00
    Madrid
    Avenida de América Coach Station
    18:30
    Santander
    Coach Station
    0
    ALSA
    Economy
    £34
  • FlixBus
    16h 45m
    0
    16:40
    Madrid
    Sur Bus Station
    09:25
    Santander
    Coach Station
    0
    FlixBus
    Economy
    £83
  • Did you know that if you travel from Madrid to Santander via Valladolid, you can save more than £18? You can find the corresponding connections below.
    • Linecar
      4h 40m
      0
      09:35
      Madrid
      Poligono 17 Rustica
      09:40
      Valladolid
      Coach Station
      0
      Linecar
      Economy
      £1
      • Waiting Time 1h 20m
    • Busbud
      3h 15m
      0
      11:00
      Valladolid
      Coach Station
      14:15
      Santander
      Coach Station
      0
      Busbud
      Economy
      £14
    Travel Time is 0h 50m shorter, and you will save £18

Cheapest bus trips Tuesday

Prices are for one way and one person
  • ALSA
    5h 50m
    0
    08:00
    Madrid
    Avenida de Aragon
    13:50
    Santander
    Coach Station
    0
    ALSA
    Economy
    £21
  • ALSA
    5h 45m
    0
    10:30
    Madrid
    Avenida de América Coach Station
    16:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £21
  • ALSA
    5h 45m
    0
    16:30
    Madrid
    Avenida de América Coach Station
    22:15
    Santander
    Coach Station
    0
    ALSA
    Economy
    £21
  • FlixBus
    16h 45m
    0
    16:40
    Madrid
    Sur Bus Station
    09:25
    Santander
    Coach Station
    0
    FlixBus
    Economy
    £71
  • Did you know that if you travel from Madrid to Santander via Valladolid, you can save more than £6? You can find the corresponding connections below.
    • Linecar
      4h 40m
      0
      09:35
      Madrid
      Poligono 17 Rustica
      09:40
      Valladolid
      Coach Station
      0
      Linecar
      Economy
      £1
      • Waiting Time 1h 20m
    • Busbud
      3h 15m
      0
      11:00
      Valladolid
      Coach Station
      14:15
      Santander
      Coach Station
      0
      Busbud
      Economy
      £14
    Travel Time is 1h 5m shorter, and you will save £6

What is the best day and time to travel by bus between Madrid and Santander?

Here is the frequency of all coach connections from Madrid to Santander. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Sunday is the busiest day, with more than 19 daily coaches from Madrid to Santander. Wednesday has instead the fewest connections, with only 7 daily coaches between Madrid and Santander.
The busiest time of the day is the Afternoon, with 41 coaches from Madrid to Santander, while Night sees the fewest connections between Madrid and Santander, with 12 offers.

All facts for Madrid to Santander bus at a glance

Compare all coach operators like ALSA and FlixBus that travel daily 14 times by bus from Madrid to Santander in one click. Book your Madrid to Santander bus ticket starting from £21!

Cheapest Bus £21
Fastest Bus 5h 30m
Earliest Coach 00:30
Latest Coach 23:30
Daily Bus Connections 14 Ø
Distance 338.8 km
Coach Companies ALSA and FlixBus

What are the cheapest coach tickets from Madrid to Santander?

Every day, 14 buses from 2 coach companies leave Madrid for Santander. Check the table below to find the cheapest prices for coach tickets for this route, starting from 16/04/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 14/04
Tuesday 15/04
Wednesday 16/04
£37
Thursday 17/04
£34
Friday 18/04
£34
Saturday 19/04
£21
Sunday 20/04
£33
Monday 21/04
£36
Tuesday 22/04
£21
Wednesday 23/04
£18
Thursday 24/04
£18
Friday 25/04
£33
Saturday 26/04
£18
Sunday 27/04
£33
Monday 28/04
£18
Tuesday 29/04
£18
Wednesday 30/04
£21
Thursday 01/05
£33
Friday 02/05
£33
Saturday 03/05
£18
Sunday 04/05
£33
Monday 05/05
£21
Tuesday 06/05
£18
Wednesday 07/05
£18
Thursday 08/05
£18
Friday 09/05
£18
Saturday 10/05
£18
Sunday 11/05

The cheapest time to travel from Madrid to Santander

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Santander, for the next 30 days.
With a price starting from £21, Tuesday is the cheapest day for a coach from Madrid to Santander. Thursday instead is the most expensive day with prices starting from £34.
Morning is the cheapest day time for bus tickets from Madrid to Santander, with £21. Night is the most expensive time of the day with prices starting from £36.

How to save money travelling from Madrid to Santander

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Madrid to Santander in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Madrid to Santander, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Madrid to Santander are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Madrid and Santander

Here is a map with all coach stations in Madrid and Santander. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Santander? Compare all modes of transports from Madrid to Santander.

All you need to know when you travel by bus from Madrid to Santander

Check all information on comfort and services on the coaches from Madrid to Santander. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Madrid to Santander bus

How much does a Madrid Santander coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Madrid Santander bus trip is available from £21 and takes 5h 50m. Compare offers and save money!

How much could I save by comparing buses from Madrid to Santander?

This connection is offered by 2 companies with ticket prices ranging from £21 to £95. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santander.

How many connections are available for the Madrid Santander route on average every day?

Each day, the bus route from Madrid to Santander is offered by roughly 14 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santander from Madrid take?

The quickest coach from Madrid to Santander is provided by ALSA and takes 5h 30m. Coach tickets for this connection cost £33. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Madrid to Santander?

The earliest bus to Santander departs from Madrid at 00:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Madrid to Santander?

The latest bus to Santander departs from Madrid at 23:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Madrid Santander route?

Passengers looking to travel from Madrid to Santander can travel with ALSA and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Madrid and Santander?

You can check all the direct connections between Madrid and Santander by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ALSA and FlixBus.

What can I take with me on the bus to Santander from Madrid?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Madrid Santander bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Santander bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Santander on your planned travel date.

Available seat classes which are offered on the bus route Madrid to Santander

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Santander

Here’s an overview of the most popular bus routes to Madrid and to Santander. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Bus from Linares to Madrid Bus from Linares to Madrid
Buses Cullera to Madrid Buses Cullera to Madrid
Torrevieja to Madrid bus Torrevieja to Madrid bus
Coach from Oviedo to Madrid Coach from Oviedo to Madrid
San Sebastian to Santander bus San Sebastian to Santander bus
Buses Oviedo to Santander Buses Oviedo to Santander
Buses Burgos to Santander Buses Burgos to Santander
Coach from Logroño to Santander Coach from Logroño to Santander
Popular Airport Transfers to Madrid and to Santander
CheckMyBus › Coaches in Spain › Coach to Madrid › Coach to Santander

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus deals, we and our partners use technical, analytical, and marketing cookies for ads personalisation. We remember your anonymized details to provide a personalized experience.