Bus and Coach from Milan to Lyon: Compare all prices

Compare all timetables for the bus from Milan to Lyon

Here is a selection of the cheapest bus trips from the schedule from Milan to Lyon from various bus operators like Itabus, FlixBus or BlaBlaCar Bus for the next days.

today

£14

tomorrow

£14

Monday

£17

Tuesday

£17

Wednesday

£16

Thursday

£19

Friday

£19

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	6h 20m	20:00	Milan	Lampugnano Bus Station	02:20	Lyon	Perrache Train Station	Economy	£14	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 20:00:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 02:20:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 20m
BlaBlaCar Bus	7h 10m	23:35	Milan	Lampugnano Bus Station	06:45	Lyon	Perrache Train Station	Economy	£14	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 23:35:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 06:45:00. 50 Economy ticket for £14 per person are available. Travel duration is 7h 10m
Itabus	6h 35m	14:55	Milan	Lampugnano Bus Station	21:30	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 21:30:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
Itabus	6h 30m	22:25	Milan	Lampugnano Bus Station	04:55	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 22:25:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 04:55:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 30m
FlixBus	7h 35m	18:00	Milan	Lampugnano Bus Station	01:35	Lyon	Perrache Bus Stop	Economy	£19	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 18:00:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 01:35:00. 50 Economy ticket for £19 per person are available. Travel duration is 7h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 35m	06:20	Milan	Lampugnano Bus Station	12:55	Lyon	Perrache Bus Stop	Premium Economy	£14	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 14/12/2025 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 12:55:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 6h 35m
Itabus	6h 35m	14:55	Milan	Lampugnano Bus Station	21:30	Lyon	Perrache Bus Stop	Premium Economy	£14	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 14/12/2025 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 21:30:00. 50 Premium Economy ticket for £14 per person are available. Travel duration is 6h 35m
BlaBlaCar Bus	8h 15m	10:35	Milan	Lampugnano Bus Station	18:50	Lyon	Perrache Train Station	Economy	£14	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 14/12/2025 10:35:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 18:50:00. 50 Economy ticket for £14 per person are available. Travel duration is 8h 15m
BlaBlaCar Bus	6h 55m	16:00	Milan	Lampugnano Bus Station	22:55	Lyon	Perrache Train Station	Economy	£14	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 14/12/2025 16:00:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 22:55:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 55m
FlixBus	6h 40m	07:30	Milan	Lampugnano Bus Station	14:10	Lyon	Perrache Bus Stop	Economy	£16	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 14/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 14:10:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 10m	09:05	Milan	Lampugnano Bus Station	16:15	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 09:05:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 16:15:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 10m
FlixBus	6h 15m	15:00	Milan	Lampugnano Bus Station	21:15	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 15:00:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 21:15:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 15m
FlixBus	6h 35m	18:00	Milan	Lampugnano Bus Station	00:35	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 18:00:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 00:35:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 35m
Itabus	6h 35m	06:20	Milan	Lampugnano Bus Station	12:55	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 12:55:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
Itabus	6h 35m	14:55	Milan	Lampugnano Bus Station	21:30	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 21:30:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 15m	05:45	Milan	Lampugnano Bus Station	12:00	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 16/12/2025 05:45:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 12:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 15m
FlixBus	7h 10m	09:05	Milan	Lampugnano Bus Station	16:15	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 16/12/2025 09:05:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 16:15:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 10m
FlixBus	6h 35m	18:00	Milan	Lampugnano Bus Station	00:35	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 16/12/2025 18:00:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 00:35:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 35m
Itabus	6h 35m	06:20	Milan	Lampugnano Bus Station	12:55	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 16/12/2025 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 12:55:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
Itabus	6h 35m	14:55	Milan	Lampugnano Bus Station	21:30	Lyon	Perrache Bus Stop	Premium Economy	£28	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 16/12/2025 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 21:30:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 6h 35m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	6h 50m	17:00	Milan	Lampugnano Bus Station	23:50	Lyon	Perrache Train Station	Economy	£16	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 17/12/2025 17:00:00 to Perrache Train Station, Lyon (France) arriving at 17/12/2025 23:50:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 50m
BlaBlaCar Bus	6h 20m	20:00	Milan	Lampugnano Bus Station	02:20	Lyon	Perrache Train Station	Economy	£16	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 17/12/2025 20:00:00 to Perrache Train Station, Lyon (France) arriving at 18/12/2025 02:20:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 20m
FlixBus	6h 15m	05:45	Milan	Lampugnano Bus Station	12:00	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 17/12/2025 05:45:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 12:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 15m
FlixBus	7h 10m	09:05	Milan	Lampugnano Bus Station	16:15	Lyon	Perrache Bus Stop	Economy	£17	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 17/12/2025 09:05:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 16:15:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 10m
Itabus	6h 35m	06:20	Milan	Lampugnano Bus Station	12:55	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 17/12/2025 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 12:55:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 35m	06:20	Milan	Lampugnano Bus Station	12:55	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 12:55:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
Itabus	6h 35m	14:55	Milan	Lampugnano Bus Station	21:30	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 21:30:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
BlaBlaCar Bus	6h 50m	10:20	Milan	Lampugnano Bus Station	17:10	Lyon	Perrache Train Station	Economy	£26	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 10:20:00 to Perrache Train Station, Lyon (France) arriving at 18/12/2025 17:10:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 50m
BlaBlaCar Bus	8h 15m	10:35	Milan	Lampugnano Bus Station	18:50	Lyon	Perrache Train Station	Economy	£26	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 10:35:00 to Perrache Train Station, Lyon (France) arriving at 18/12/2025 18:50:00. 50 Economy ticket for £26 per person are available. Travel duration is 8h 15m
FlixBus	7h 10m	09:05	Milan	Lampugnano Bus Station	16:15	Lyon	Perrache Bus Stop	Economy	£30	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 09:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 16:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 7h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	6h 35m	06:20	Milan	Lampugnano Bus Station	12:55	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 06:20:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 12:55:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
Itabus	6h 35m	14:55	Milan	Lampugnano Bus Station	21:30	Lyon	Perrache Bus Stop	Premium Economy	£19	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 14:55:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 21:30:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 6h 35m
BlaBlaCar Bus	6h 35m	18:50	Milan	Lampugnano Bus Station	01:25	Lyon	Perrache Train Station	Economy	£26	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 18:50:00 to Perrache Train Station, Lyon (France) arriving at 20/12/2025 01:25:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 35m
BlaBlaCar Bus	8h 15m	10:35	Milan	Lampugnano Bus Station	18:50	Lyon	Perrache Train Station	Economy	£31	A Bus from BlaBlaCar Bus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 10:35:00 to Perrache Train Station, Lyon (France) arriving at 19/12/2025 18:50:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 15m
FlixBus	6h 40m	07:30	Milan	Lampugnano Bus Station	14:10	Lyon	Perrache Bus Stop	Economy	£32	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 14:10:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 40m

Best Price Offer: The price for the cheapest coach from Milan to Lyon is £14 on 13/12/2025. Flexible travellers save on ticket prices.

Frequency of bus connections between Milan and Lyon

See here how frequent the connections between Milan and Lyon are, during different times and days of the week.

Friday is the busiest day, with more than 36 daily coaches from Milan to Lyon. Tuesday has instead the fewest connections, with only 14 daily coaches between Milan and Lyon.

The busiest time of the day is the Morning, with 61 coaches from Milan to Lyon, while Night sees the fewest connections between Milan and Lyon, with 10 offers.

Facts about coaches from Milan to Lyon

Compare all providers like Itabus, FlixBus and BlaBlaCar Bus that travel 25 times every day by bus from Milan to Lyon in one click! Book your bus ticket from Milan to Lyon starting from £14!

Cheapest Bus	£14
Fastest Bus	6h 10m
Earliest Coach	14:55
Latest Coach	23:45
Daily Bus Connections	25 Ø
Distance	339.9 km
Coach Companies	Itabus, FlixBus, BlaBlaCar Bus and Union Ivkoni

Cheapest coach connections from Milan to Lyon

Every day, 25 buses from 4 coach companies leave Milan for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 13/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 08/12

Tuesday 09/12

Wednesday 10/12

Thursday 11/12

Friday 12/12

Saturday 13/12

£14

Sunday 14/12

£30

Monday 15/12

£14

Tuesday 16/12

£14

Wednesday 17/12

£16

Thursday 18/12

£19

Friday 19/12

£19

Saturday 20/12

£19

Sunday 21/12

£19

Monday 22/12

£19

Tuesday 23/12

£33

Wednesday 24/12

£26

Thursday 25/12

£22

Friday 26/12

£33

Saturday 27/12

£19

Sunday 28/12

£39

Monday 29/12

£49

Tuesday 30/12

£39

Wednesday 31/12

£31

Thursday 01/01

£26

Friday 02/01

£63

Saturday 03/01

£44

Sunday 04/01

The cheapest time to travel from Milan to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Lyon, for the next 30 days.

With a price starting from £14, Saturday is the cheapest day for a coach from Milan to Lyon. Friday instead is the most expensive day with prices starting from £19.

Morning is the cheapest day time for bus tickets from Milan to Lyon, with £14. Night is the most expensive time of the day with prices starting from £14.

How to save money travelling from Milan to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Lyon are also emptier.

Latest reviews for coach companies on the route Milan - Lyon

Brian, 22/11/2025

I can 100% back up the comments above - and then some because at a 30 minute stopover we came out after 20 minutes to find him driving off slowly, teasing us while looking through the closed door. For ... I can 100% back up the comments above - and then some because at a 30 minute stopover we came out after 20 minutes to find him driving off slowly, teasing us while looking through the closed door. Forced us to run and fall in the snow (lol) all because he was very late (2hrs in the end) and their drivers do seem to be rude and agressive. I will never give them a cent again.

All bus stations and stops in Milan and Lyon

The map below shows you where to find all the bus stations in Milan and Lyon.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Duomo Bus Stop

Piazza del Duomo

Central Bus Station

Perrache Bus Stop

Cours de Verdun 14

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Jean-Macé Train Station

Maison Carrée Bus Stop

Les Charrières 69570

Vaise Train Station

Rue du 24 Mars 1852

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Lyon? Compare all modes of transports from Milan to Lyon.

Service and Comfort on the bus from Milan to Lyon

Want to know which seat classes are available on the coaches from Milan to Lyon? Or which bus companies serve the route Milan to Lyon? Below you will find answers to your questions.

FAQs about the Milan to Lyon bus

How much does a Milan - Lyon coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Milan - Lyon bus trip is available from £14 and takes 6h 20m. Compare offers and save money!

How much could I save by comparing buses from Milan to Lyon?

The connection Milan to Lyon is offered by 4 companies with ticket prices ranging from £14 to £55. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Milan - Lyon route on average every day?

Each day, the bus route from Milan to Lyon is offered by roughly 25 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Lyon from Milan take?

The quickest coach from Milan to Lyon is provided by FlixBus and takes 6h 10m. Coach tickets for this connection cost £20. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Milan to Lyon?

The earliest bus to Lyon departs from Milan at 14:55. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Milan to Lyon?

The latest bus to Lyon departs from Milan at 23:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Milan - Lyon route?

Passengers looking to travel from Milan to Lyon can travel with Itabus, FlixBus and BlaBlaCar Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Milan and Lyon?

You can check all the direct connections between Milan and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, FlixBus and BlaBlaCar Bus.

What can I take with me on the bus to Lyon from Milan?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Milan Lyon bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Lyon on your planned travel date.

Available seat classes which are offered on the bus route Milan to Lyon

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Lyon

Here’s an overview of the most popular bus routes to Milan and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!