Which bus from Milan to Palermo is the cheapest?

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Which bus from Milan to Palermo is the best?

Check the bus schedule for Milan to Palermo. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Autoservizi Salemi. To see the full timetable for all coaches just use or search and compare.

today
£89
tomorrow
£91
Monday
£72
Tuesday
£66
Wednesday
£91
Thursday
£58
Friday
£100

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 5m 12:55 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £89
FlixBus 22h 55m 15:30 Milan Lampugnano Bus Station 14:25 Palermo Via Tommaso Fazello Bus Stop  Economy £119
FlixBus 23h 40m 14:45 Milan San Donato Bus Station 14:25 Palermo Via Tommaso Fazello Bus Stop  Economy £125
FlixBus 25h 20m 09:40 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £126
  • Did you know that if you travel from Milan to Palermo via Sesto San Giovanni, you can save more than £-22? You will find the corresponding connections below.
    • FlixBus
      27h 55m
      Milan
      8 km
      07:05
      Sesto San Giovanni
      Sesto 1° Maggio FS
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £111

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 5m 12:55 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £91
FlixBus 25h 0m 10:00 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £106
FlixBus 22h 55m 15:30 Milan Lampugnano Bus Station 14:25 Palermo Via Tommaso Fazello Bus Stop  Economy £143
FlixBus 23h 40m 14:45 Milan San Donato Bus Station 14:25 Palermo Via Tommaso Fazello Bus Stop  Economy £147
  • Did you know that if you travel from Milan to Palermo via Sesto San Giovanni, you can save more than £-14? You will find the corresponding connections below.
    • FlixBus
      27h 55m
      Milan
      8 km
      07:05
      Sesto San Giovanni
      Sesto 1° Maggio FS
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £105
  • Did you know that if you travel from Milan to Palermo via Piacenza, you can save more than £23? You can find the corresponding connections below.
    • Busbud
      31h 35m
      0
      06:50
      Milan
      San Donato Bus Station
      07:40
      Piacenza
      Via Portapuglia
      0
      Busbud
      Premium Economy
      £8
      • Waiting Time 6h 5m
    • FlixBus
      24h 40m
      0
      13:45
      Piacenza
      Via Cremona
      14:25
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £59
    Travel time is 9h 30m longer, but you will save £23

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 5m 12:55 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £72
FlixBus 25h 20m 09:40 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £91
FlixBus 22h 55m 15:30 Milan Lampugnano Bus Station 14:25 Palermo Via Tommaso Fazello Bus Stop  Economy £93
FlixBus 23h 40m 14:45 Milan San Donato Bus Station 14:25 Palermo Via Tommaso Fazello Bus Stop  Economy £97

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 5m 12:55 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £66
FlixBus 26h 10m 08:50 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £81
FlixBus 22h 55m 15:30 Milan Lampugnano Bus Station 14:25 Palermo Via Tommaso Fazello Bus Stop  Economy £92

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 5m 12:55 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £91
FlixBus 26h 10m 08:50 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £95
  • Did you know that if you travel from Milan to Palermo via Piacenza, you can save more than £23? You can find the corresponding connections below.
    • Busbud
      31h 35m
      0
      06:50
      Milan
      San Donato Bus Station
      07:40
      Piacenza
      Via Portapuglia
      0
      Busbud
      Premium Economy
      £8
      • Waiting Time 6h 5m
    • FlixBus
      24h 40m
      0
      13:45
      Piacenza
      Via Cremona
      14:25
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      FlixBus
      Economy
      £59
    Travel time is 9h 30m longer, but you will save £23

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 20m 09:40 Milan San Donato Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £58
FlixBus 25h 25m 15:30 Milan Lampugnano Bus Station 16:55 Palermo Via Tommaso Fazello Bus Stop  Economy £58
FlixBus 22h 5m 12:55 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £62

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autoservizi Salemi 21h 45m 10:00 Milan Lampugnano Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Basic £100
Autoservizi Salemi 21h 0m 10:45 Milan San Donato Bus Station 07:45 Palermo Via Tommaso Fazello Bus Stop  Basic £100
FlixBus 22h 5m 12:55 Milan Lampugnano Bus Station 11:00 Palermo Via Tommaso Fazello Bus Stop  Economy £117
Autoservizi Salemi 21h 45m 18:00 Milan Lampugnano Bus Station 15:45 Palermo Via Tommaso Fazello Bus Stop  Basic £133
FlixBus 22h 5m 13:10 Milan Lampugnano Bus Station 11:15 Palermo Via Tommaso Fazello Bus Stop  Economy £140
  • Did you know that if you travel from Milan to Palermo via Sesto San Giovanni, you can save more than £-54? You will find the corresponding connections below.
    • FlixBus
      27h 55m
      Milan
      8 km
      07:05
      Sesto San Giovanni
      Sesto 1° Maggio FS
      11:00
      Palermo
      Via Tommaso Fazello Bus Stop
      0 km
      FlixBus
      Economy
      £154
  • Did you know that if you travel from Milan to Palermo via Piacenza, you can save more than £15? You can find the corresponding connections below.
    • Busbud
      24h 55m
      0
      06:50
      Milan
      San Donato Bus Station
      07:40
      Piacenza
      Via Portapuglia
      0
      Busbud
      Premium Economy
      £8
      • Waiting Time 3h 50m
    • Distribusion
      20h 15m
      0
      11:30
      Piacenza
      Via Portapuglia
      07:45
      Palermo
      Via Tommaso Fazello Bus Stop
      0
      Distribusion
      Basic
      £76
    Travel time is 3h 55m longer, but you will save £15

Best Price Offer: The price for the cheapest coach from Milan to Palermo is £58 on 18/12/2025. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Milan and Palermo?

Here is the frequency of all coach connections from Milan to Palermo. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Friday is the busiest day, with more than 15 daily coaches from Milan to Palermo. Wednesday has instead the fewest connections, with only 2 daily coaches between Milan and Palermo.
The busiest time of the day is the Afternoon, with 20 coaches from Milan to Palermo, while Evening sees the fewest connections between Milan and Palermo, with 4 offers.

All facts for Milan to Palermo bus at a glance

Compare all coach operators like FlixBus and Autoservizi Salemi that travel daily 5 times by bus from Milan to Palermo in one click. Book your Milan to Palermo bus ticket starting from £58!

Cheapest Bus £58
Fastest Bus 21h 0m
Earliest Coach 09:40
Latest Coach 18:45
Daily Bus Connections 5 Ø
Distance 887.2 km
Coach Companies FlixBus and Autoservizi Salemi

What are the cheapest coach tickets from Milan to Palermo?

Every day, 5 buses from 2 coach companies leave Milan for Palermo. Check the table below to find the cheapest prices for coach tickets for this route, starting from 13/12/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 08/12
Tuesday 09/12
Wednesday 10/12
Thursday 11/12
Friday 12/12
Saturday 13/12
£89
Sunday 14/12
£91
Monday 15/12
£72
Tuesday 16/12
£66
Wednesday 17/12
£91
Thursday 18/12
£58
Friday 19/12
£117
Saturday 20/12
£140
Sunday 21/12
£136
Monday 22/12
£136
Tuesday 23/12
£144
Wednesday 24/12
£102
Thursday 25/12
£75
Friday 26/12
Saturday 27/12
£87
Sunday 28/12
£91
Monday 29/12
£85
Tuesday 30/12
£86
Wednesday 31/12
£94
Thursday 01/01
Friday 02/01
£65
Saturday 03/01
£62
Sunday 04/01

The cheapest time to travel from Milan to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Palermo, for the next 30 days.
With a price starting from £56, Monday is the cheapest day for a coach from Milan to Palermo. Wednesday instead is the most expensive day with prices starting from £91.
Morning is the cheapest day time for bus tickets from Milan to Palermo, with £58. Evening is the most expensive time of the day with prices starting from £131.

How to save money travelling from Milan to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Milan to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Palermo are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Milan and Palermo

Here is a map with all coach stations in Milan and Palermo. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Palermo? Compare all modes of transports from Milan to Palermo.

All you need to know when you travel by bus from Milan to Palermo

Check all information on comfort and services on the coaches from Milan to Palermo. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Milan to Palermo bus

How much does a Milan Palermo coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Milan Palermo bus trip is available from £58 and takes 25h 20m. Compare offers and save money!

How much could I save by comparing buses from Milan to Palermo?

This connection is offered by 2 companies with ticket prices ranging from £58 to £171. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Palermo.

How many connections are available for the Milan Palermo route on average every day?

Each day, the bus route from Milan to Palermo is offered by roughly 5 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Palermo from Milan take?

The quickest coach from Milan to Palermo is provided by Autoservizi Salemi and takes 21h 0m. Coach tickets for this connection cost £100. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Milan to Palermo?

The earliest bus to Palermo departs from Milan at 09:40. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Milan to Palermo?

The latest bus to Palermo departs from Milan at 18:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Milan Palermo route?

Passengers looking to travel from Milan to Palermo can travel with FlixBus and Autoservizi Salemi. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Milan and Palermo?

You can check all the direct connections between Milan and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Autoservizi Salemi.

What can I take with me on the bus to Palermo from Milan?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Milan Palermo bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Palermo on your planned travel date.

How does CheckMyBus find the best coach deals from Milan to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Milan and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Palermo?

Prices and availability for 5 trips between Milan and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Palermo

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Palermo

Here’s an overview of the most popular bus routes to Milan and to Palermo. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Coach to Milan from Venice Coach to Milan from Venice
Bus to Milan from Rome Bus to Milan from Rome
Coach to Milan from Verona Coach to Milan from Verona
Coach to Milan from Como Coach to Milan from Como
Buses Taormina to Palermo Buses Taormina to Palermo
Bus to Palermo from Catania Bus to Palermo from Catania
Trapani to Palermo bus Trapani to Palermo bus
Bus to Palermo from Agrigento Bus to Palermo from Agrigento
Popular Airport Transfers to Milan and to Palermo
CheckMyBus › Coaches in Italy › Coach to Milan › Coach to Palermo

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