Which bus from Milan to Siena is the best?
Check the bus schedule for Milan to Siena. Here is a selection of the cheapest coach trips for the next days from bus operators like Itabus or FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 6h 35m | 08:20 | Milan | Lampugnano Bus Station | 14:55 | Siena | Train Station | Economy | £11 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 08:20:00 to Train Station, Siena (Italy) arriving at 13/12/2025 14:55:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 35m
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| FlixBus | 6h 0m | 16:20 | Milan | Lampugnano Bus Station | 22:20 | Siena | Train Station | Economy | £11 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 16:20:00 to Train Station, Siena (Italy) arriving at 13/12/2025 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 0m
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| FlixBus | 5h 15m | 17:05 | Milan | San Donato Bus Station | 22:20 | Siena | Train Station | Economy | £11 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 13/12/2025 17:05:00 to Train Station, Siena (Italy) arriving at 13/12/2025 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 5h 15m
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| Itabus | 6h 5m | 06:00 | Milan | Lampugnano Bus Station | 12:05 | Siena | Train Station | Premium Economy | £13 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 13/12/2025 12:05:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 5m
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| Itabus | 6h 30m | 22:40 | Milan | Lampugnano Bus Station | 05:10 | Siena | Train Station | Premium Economy | £13 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 13/12/2025 22:40:00 to Train Station, Siena (Italy) arriving at 14/12/2025 05:10:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 15m | 06:50 | Milan | San Donato Bus Station | 12:05 | Siena | Train Station | Premium Economy | £25 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 14/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 14/12/2025 12:05:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 5h 15m
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| Itabus | 6h 5m | 06:00 | Milan | Lampugnano Bus Station | 12:05 | Siena | Train Station | Premium Economy | £25 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 14/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 14/12/2025 12:05:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 6h 5m
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| Itabus | 5h 15m | 00:45 | Milan | San Donato Bus Station | 06:00 | Siena | Train Station | Economy | £28 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 14/12/2025 00:45:00 to Train Station, Siena (Italy) arriving at 14/12/2025 06:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 5h 15m
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| Itabus | 6h 5m | 23:55 | Milan | Lampugnano Bus Station | 06:00 | Siena | Train Station | Premium Economy | £28 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 14/12/2025 23:55:00 to Train Station, Siena (Italy) arriving at 15/12/2025 06:00:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 6h 5m
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| Itabus | 5h 40m | 23:30 | Milan | San Donato Bus Station | 05:10 | Siena | Train Station | Economy | £31 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 14/12/2025 23:30:00 to Train Station, Siena (Italy) arriving at 15/12/2025 05:10:00. 50 Economy ticket for £31 per person are available. Travel duration is 5h 40m
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Distribusion7h 30m011:15MilanLampugnano Bus Station15:55FlorenceVilla Costanza Bus Station0Premium EconomyA Bus from Distribusion goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 11:15:00 to Villa Costanza Bus Station, Florence (Italy) arriving at 15/12/2025 15:55:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 4h 40m
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Distribusion0h 55m017:50FlorenceVilla Costanza Bus Station18:45SienaTrain Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 17:50:00 to Train Station, Siena (Italy) arriving at 15/12/2025 18:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 0h 55m
Waiting Time 1h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 6h 0m | 16:20 | Milan | Lampugnano Bus Station | 22:20 | Siena | Train Station | Economy | £11 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 16:20:00 to Train Station, Siena (Italy) arriving at 15/12/2025 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 0m
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| FlixBus | 5h 15m | 17:05 | Milan | San Donato Bus Station | 22:20 | Siena | Train Station | Economy | £11 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 15/12/2025 17:05:00 to Train Station, Siena (Italy) arriving at 15/12/2025 22:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 5h 15m
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| FlixBus | 7h 25m | 08:15 | Milan | Lampugnano Bus Station | 15:40 | Siena | Train Station | Economy | £13 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 08:15:00 to Train Station, Siena (Italy) arriving at 15/12/2025 15:40:00. 50 Economy ticket for £13 per person are available. Travel duration is 7h 25m
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| Itabus | 5h 15m | 06:50 | Milan | San Donato Bus Station | 12:05 | Siena | Train Station | Premium Economy | £13 |
A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 15/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 15/12/2025 12:05:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 15m
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| Itabus | 6h 5m | 06:00 | Milan | Lampugnano Bus Station | 12:05 | Siena | Train Station | Premium Economy | £13 |
A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 15/12/2025 06:00:00 to Train Station, Siena (Italy) arriving at 15/12/2025 12:05:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 45m | 15:30 | Milan | Lampugnano Bus Station | 21:15 | Siena | Train Station | Economy | £14 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 15:30:00 to Train Station, Siena (Italy) arriving at 18/12/2025 21:15:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 45m
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| FlixBus | 7h 40m | 12:00 | Milan | Lampugnano Bus Station | 19:40 | Siena | Train Station | Economy | £15 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 18/12/2025 19:40:00. 50 Economy ticket for £15 per person are available. Travel duration is 7h 40m
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| FlixBus | 6h 35m | 08:20 | Milan | Lampugnano Bus Station | 14:55 | Siena | Train Station | Economy | £16 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 08:20:00 to Train Station, Siena (Italy) arriving at 18/12/2025 14:55:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 35m
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| FlixBus | 4h 55m | 00:35 | Milan | Lampugnano Bus Station | 05:30 | Siena | Train Station | Economy | £18 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 18/12/2025 00:35:00 to Train Station, Siena (Italy) arriving at 18/12/2025 05:30:00. 50 Economy ticket for £18 per person are available. Travel duration is 4h 55m
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| FlixBus | 4h 20m | 01:10 | Milan | San Donato Bus Station | 05:30 | Siena | Train Station | Economy | £18 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 18/12/2025 01:10:00 to Train Station, Siena (Italy) arriving at 18/12/2025 05:30:00. 50 Economy ticket for £18 per person are available. Travel duration is 4h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 6h 15m | 06:15 | Milan | Lampugnano Bus Station | 12:30 | Siena | Train Station | Economy | £14 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 06:15:00 to Train Station, Siena (Italy) arriving at 19/12/2025 12:30:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 15m
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| FlixBus | 5h 40m | 06:50 | Milan | San Donato Bus Station | 12:30 | Siena | Train Station | Economy | £14 |
A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 19/12/2025 06:50:00 to Train Station, Siena (Italy) arriving at 19/12/2025 12:30:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 40m
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| FlixBus | 7h 25m | 08:15 | Milan | Lampugnano Bus Station | 15:40 | Siena | Train Station | Economy | £17 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 08:15:00 to Train Station, Siena (Italy) arriving at 19/12/2025 15:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 25m
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| FlixBus | 7h 40m | 12:00 | Milan | Lampugnano Bus Station | 19:40 | Siena | Train Station | Economy | £17 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 12:00:00 to Train Station, Siena (Italy) arriving at 19/12/2025 19:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 40m
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| FlixBus | 4h 55m | 00:35 | Milan | Lampugnano Bus Station | 05:30 | Siena | Train Station | Economy | £19 |
A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 19/12/2025 00:35:00 to Train Station, Siena (Italy) arriving at 19/12/2025 05:30:00. 50 Economy ticket for £19 per person are available. Travel duration is 4h 55m
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Best Price Offer: The price for the cheapest coach from Milan to Siena is £8 on 12/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Milan and Siena?
All facts for Milan to Siena bus at a glance
Compare all coach operators like Itabus and FlixBus that travel daily 24 times by bus from Milan to Siena in one click. Book your Milan to Siena bus ticket starting from £8!
| Cheapest Bus | £8 |
| Fastest Bus | 4h 20m |
| Earliest Coach | 06:00 |
| Latest Coach | 17:05 |
| Daily Bus Connections | 24 Ø |
| Distance | 293.3 km |
| Coach Companies | Itabus and FlixBus |
What are the cheapest coach tickets from Milan to Siena?
Every day, 24 buses from 2 coach companies leave Milan for Siena. Check the table below to find the cheapest prices for coach tickets for this route, starting from 13/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Milan to Siena
How to save money travelling from Milan to Siena
Book the ticket from Milan to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Milan to Siena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Milan to Siena are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Milan to Siena?
Itabus from Milan to Siena
Here you will find the key facts about the Itabus bus route Milan to Siena:
| Cheapest Price | £13 |
| Fastest Coach | 5h 15m |
| Earliest Coach | 06:00 |
| Last Coach | 23:55 |
| Daily Connections | 25 Ø |
| Found on | 07/12/2025 |
All bus stations and stops in Milan and Siena
Here is a map with all coach stations in Milan and Siena. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Milan to Siena
FAQs for Milan to Siena bus
How much does a Milan Siena coach trip cost?
How much could I save by comparing buses from Milan to Siena?
How many connections are available for the Milan Siena route on average every day?
How long does a bus to Siena from Milan take?
What time is the first bus from Milan to Siena?
What time is the last coach from Milan to Siena?
Which bus companies serve the Milan Siena route?
Is there a direct bus between Milan and Siena?
What can I take with me on the bus to Siena from Milan?
What equipment is available for the Milan Siena bus route?
How does CheckMyBus find the best coach deals from Milan to Siena?
How does CheckMyBus technology work for trips from Milan to Siena?
Available seat classes which are offered on the bus route Milan to Siena
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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