Bus tickets Prague to Lyon from £41

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Compare all timetables for the bus from Prague to Lyon

Here is a selection of the cheapest bus trips from the schedule from Prague to Lyon from various bus operators like FlixBus for the next days.
today
from £56
tomorrow
from £54
Sunday
from £56
Monday
from £45
Tuesday
from £43
Wednesday
from £41
Thursday
from £42

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    16h 45m
    0
    16:15
    Prague
    Wilsonova Coach Station
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £56
  • FlixBus
    17h 0m
    0
    16:00
    Prague
    ÚAN Florenc
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £56
  • FlixBus
    19h 25m
    0
    03:50
    Prague
    Wilsonova Coach Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £59
  • FlixBus
    19h 5m
    0
    04:10
    Prague
    Na Knížecí Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £59
  • FlixBus
    19h 10m
    0
    13:05
    Prague
    Zličín
    08:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £60
  • Did you know that if you travel from Prague to Lyon via Zurich, you can save more than £13? You can find the corresponding connections below.
    • FlixBus
      22h 35m
      0
      16:15
      Prague
      Wilsonova Coach Station
      02:35
      Zurich
      Central Bus Station Sihlquai
      0
      FlixBus
      Economy
      £28
      • Waiting Time 6h 0m
    • RegioJet
      6h 15m
      0
      08:35
      Zurich
      Central Bus Station Sihlquai
      14:50
      Lyon
      Perrache Bus Stop
      0
      RegioJet
      Economy
      £15
    Travel time is 5h 50m longer, but you will save £13

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    19h 25m
    0
    03:50
    Prague
    Wilsonova Coach Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £54
  • FlixBus
    20h 35m
    0
    09:00
    Prague
    Wilsonova Coach Station
    05:35
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £54
  • FlixBus
    20h 10m
    0
    13:05
    Prague
    Wilsonova Coach Station
    09:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £54
  • FlixBus
    19h 5m
    0
    04:10
    Prague
    Na Knížecí Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £54
  • FlixBus
    20h 35m
    0
    09:10
    Prague
    Na Knížecí Station
    05:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £55
  • Did you know that if you travel from Prague to Lyon via Zurich, you can save more than £11? You can find the corresponding connections below.
    • FlixBus
      22h 35m
      0
      16:15
      Prague
      Wilsonova Coach Station
      02:35
      Zurich
      Central Bus Station Sihlquai
      0
      FlixBus
      Economy
      £28
      • Waiting Time 6h 0m
    • RegioJet
      6h 15m
      0
      08:35
      Zurich
      Central Bus Station Sihlquai
      14:50
      Lyon
      Perrache Bus Stop
      0
      RegioJet
      Economy
      £15
    Travel time is 3h 30m longer, but you will save £11

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    19h 25m
    0
    04:50
    Prague
    Wilsonova Coach Station
    00:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £56
  • FlixBus
    19h 5m
    0
    05:10
    Prague
    Na Knížecí Station
    00:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £56
  • FlixBus
    14h 35m
    0
    21:50
    Prague
    Na Knížecí Station
    12:25
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £58
  • FlixBus
    16h 35m
    0
    07:40
    Prague
    ÚAN Florenc
    00:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £58
  • FlixBus
    15h 0m
    0
    21:25
    Prague
    ÚAN Florenc
    12:25
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £58
  • Did you know that if you travel from Prague to Lyon via Zurich, you can save more than £12? You can find the corresponding connections below.
    • FlixBus
      19h 45m
      0
      19:05
      Prague
      Wilsonova Coach Station
      04:55
      Zurich
      Central Bus Station Sihlquai
      0
      FlixBus
      Economy
      £29
      • Waiting Time 3h 40m
    • RegioJet
      6h 15m
      0
      08:35
      Zurich
      Central Bus Station Sihlquai
      14:50
      Lyon
      Perrache Bus Stop
      0
      RegioJet
      Economy
      £15
    Travel time is 5h 10m longer, but you will save £12

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    19h 25m
    0
    03:50
    Prague
    Wilsonova Coach Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £45
  • FlixBus
    19h 5m
    0
    04:10
    Prague
    Na Knížecí Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £45
  • FlixBus
    19h 35m
    0
    09:10
    Prague
    Na Knížecí Station
    04:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £46
  • FlixBus
    17h 10m
    0
    15:05
    Prague
    Zličín
    08:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £46
  • FlixBus
    16h 45m
    0
    16:15
    Prague
    Wilsonova Coach Station
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £47

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    21h 40m
    0
    12:50
    Prague
    Hradčanská
    10:30
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £43
  • FlixBus
    17h 10m
    0
    15:05
    Prague
    Zličín
    08:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £43
  • FlixBus
    16h 45m
    0
    16:15
    Prague
    Wilsonova Coach Station
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • FlixBus
    17h 0m
    0
    16:00
    Prague
    ÚAN Florenc
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • FlixBus
    19h 25m
    0
    03:50
    Prague
    Wilsonova Coach Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £45

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    17h 10m
    0
    15:05
    Prague
    Zličín
    08:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £41
  • FlixBus
    19h 10m
    0
    13:05
    Prague
    Wilsonova Coach Station
    08:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £42
  • FlixBus
    16h 45m
    0
    16:15
    Prague
    Wilsonova Coach Station
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • FlixBus
    14h 35m
    0
    21:50
    Prague
    Na Knížecí Station
    12:25
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • FlixBus
    17h 0m
    0
    16:00
    Prague
    ÚAN Florenc
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    19h 25m
    0
    03:50
    Prague
    Wilsonova Coach Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £42
  • FlixBus
    19h 10m
    0
    13:05
    Prague
    Wilsonova Coach Station
    08:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £42
  • FlixBus
    19h 5m
    0
    04:10
    Prague
    Na Knížecí Station
    23:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £42
  • FlixBus
    17h 10m
    0
    15:05
    Prague
    Zličín
    08:15
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £42
  • FlixBus
    16h 45m
    0
    16:15
    Prague
    Wilsonova Coach Station
    09:00
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44

Frequency of bus connections between Prague and Lyon

See here how frequent the connections between Prague and Lyon are, during different times and days of the week.
Tuesday is the busiest day, with more than 15 daily coaches from Prague to Lyon. Wednesday has instead the fewest connections, with only 12 daily coaches between Prague and Lyon.
The busiest time of the day is the Afternoon, with 44 coaches from Prague to Lyon, while Evening sees the fewest connections between Prague and Lyon, with 14 offers.

Facts about coaches from Prague to Lyon

Compare all providers like FlixBus that travel 13 times every day by bus from Prague to Lyon in one click! Book your bus ticket from Prague to Lyon starting from £41!

Cheapest Bus £41
Fastest Bus 14h 35m
Earliest Coach 03:50
Latest Coach 21:50
Daily Bus Connections 13 Ø
Distance 860.7 km
Coach Companies FlixBus

Cheapest coach connections from Prague to Lyon

Every day, 13 buses from 1 coach companies leave Prague for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 29/03/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 24/03
Tuesday 25/03
Wednesday 26/03
Thursday 27/03
Friday 28/03
£56
Saturday 29/03
£54
Sunday 30/03
£56
Monday 31/03
£45
Tuesday 01/04
£43
Wednesday 02/04
£41
Thursday 03/04
£42
Friday 04/04
£47
Saturday 05/04
£44
Sunday 06/04
£51
Monday 07/04
£39
Tuesday 08/04
£39
Wednesday 09/04
£38
Thursday 10/04
£41
Friday 11/04
£46
Saturday 12/04
£42
Sunday 13/04
£53
Monday 14/04
£41
Tuesday 15/04
£44
Wednesday 16/04
£49
Thursday 17/04
£58
Friday 18/04
£67
Saturday 19/04
£53
Sunday 20/04

The cheapest time to travel from Prague to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Lyon, for the next 30 days.
With a price starting from £41, Wednesday is the cheapest day for a coach from Prague to Lyon. Friday instead is the most expensive day with prices starting from £56.
Afternoon is the cheapest day time for bus tickets from Prague to Lyon, with £41. Morning is the most expensive time of the day with prices starting from £45.

How to save money travelling from Prague to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Lyon are also emptier.

Beloved bus companies from Prague to Lyon

These are the most booked bus companies between Prague to Lyon from our users.

FlixBus from Prague to Lyon

FlixBus

Here you will find the key facts about the FlixBus bus route Prague to Lyon:

Cheapest Price £41
Fastest Coach 14h 35m
Earliest Coach 03:50
Last Coach 21:50
Daily Connections 13 Ø
Found on 27/03/2025

All bus stations and stops in Prague and Lyon

The map below shows you where to find all the bus stations in Prague and Lyon.

Service and Comfort on the bus from Prague to Lyon

Want to know which seat classes are available on the coaches from Prague to Lyon? Or which bus companies serve the route Prague to Lyon? Below you will find answers to your questions.

FAQs about the Prague to Lyon bus

How much does a Prague - Lyon coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Prague - Lyon bus trip is available from £41 and takes 17h 10m. Compare offers and save money!

How much could I save by comparing buses from Prague to Lyon?

The connection Prague to Lyon is offered by 1 companies with ticket prices ranging from £41 to £104. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Prague - Lyon route on average every day?

Each day, the bus route from Prague to Lyon is offered by roughly 13 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Lyon from Prague take?

The quickest coach from Prague to Lyon is provided by FlixBus and takes 14h 35m. Coach tickets for this connection cost £89. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Prague to Lyon?

The earliest bus to Lyon departs from Prague at 03:50. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Prague to Lyon?

The latest bus to Lyon departs from Prague at 21:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Prague - Lyon route?

Passengers looking to travel from Prague to Lyon can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Prague and Lyon?

You can check all the direct connections between Prague and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Lyon from Prague?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Prague Lyon bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Lyon on your planned travel date.

Available seat classes which are offered on the bus route Prague to Lyon

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Lyon

Here’s an overview of the most popular bus routes to Prague and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Coach Moutiers to Lyon Coach Moutiers to Lyon
Buses Nantes to Lyon Buses Nantes to Lyon
London to Lyon bus London to Lyon bus
Bus from Rome to Lyon Bus from Rome to Lyon
Popular Airport Transfers to Prague and to Lyon
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