Bus and Coach from Prague to Mannheim: Compare all prices

Compare all timetables for the bus from Prague to Mannheim

Here is a selection of the cheapest bus trips from the schedule from Prague to Mannheim from various bus operators like FlixBus for the next days.

today

£57

tomorrow

Tuesday

Wednesday

£50

Thursday

Friday

£52

Saturday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 50m	17:15	Prague	ÚAN Florenc	01:05	Mannheim	Central Coach Station	Economy	£57	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 21/12/2025 17:15:00 to Central Coach Station, Mannheim (Germany) arriving at 22/12/2025 01:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 7h 50m
FlixBus	7h 20m	17:45	Prague	Na Knížecí Station	01:05	Mannheim	Central Coach Station	Economy	£57	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 17:45:00 to Central Coach Station, Mannheim (Germany) arriving at 22/12/2025 01:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 7h 20m
FlixBus	6h 45m	20:15	Prague	ÚAN Florenc	03:00	Mannheim	Central Coach Station	Economy	£63	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 21/12/2025 20:15:00 to Central Coach Station, Mannheim (Germany) arriving at 22/12/2025 03:00:00. 50 Economy ticket for £63 per person are available. Travel duration is 6h 45m
FlixBus	6h 20m	20:40	Prague	Na Knížecí Station	03:00	Mannheim	Central Coach Station	Economy	£63	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 20:40:00 to Central Coach Station, Mannheim (Germany) arriving at 22/12/2025 03:00:00. 50 Economy ticket for £63 per person are available. Travel duration is 6h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 50m	17:15	Prague	ÚAN Florenc	01:05	Mannheim	Central Coach Station	Economy	£50	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 24/12/2025 17:15:00 to Central Coach Station, Mannheim (Germany) arriving at 25/12/2025 01:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 7h 50m
FlixBus	7h 20m	17:45	Prague	Na Knížecí Station	01:05	Mannheim	Central Coach Station	Economy	£50	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/12/2025 17:45:00 to Central Coach Station, Mannheim (Germany) arriving at 25/12/2025 01:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 7h 20m
FlixBus	6h 45m	20:15	Prague	ÚAN Florenc	03:00	Mannheim	Central Coach Station	Economy	£51	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 24/12/2025 20:15:00 to Central Coach Station, Mannheim (Germany) arriving at 25/12/2025 03:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 6h 45m
FlixBus	6h 20m	20:40	Prague	Na Knížecí Station	03:00	Mannheim	Central Coach Station	Economy	£51	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/12/2025 20:40:00 to Central Coach Station, Mannheim (Germany) arriving at 25/12/2025 03:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 6h 20m
FlixBus	8h 0m	07:35	Prague	ÚAN Florenc	15:35	Mannheim	Central Coach Station	Economy	£59	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 24/12/2025 07:35:00 to Central Coach Station, Mannheim (Germany) arriving at 24/12/2025 15:35:00. 50 Economy ticket for £59 per person are available. Travel duration is 8h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 0m	07:35	Prague	ÚAN Florenc	15:35	Mannheim	Central Coach Station	Economy	£52	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 26/12/2025 07:35:00 to Central Coach Station, Mannheim (Germany) arriving at 26/12/2025 15:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 0m
FlixBus	7h 50m	17:15	Prague	ÚAN Florenc	01:05	Mannheim	Central Coach Station	Economy	£52	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 26/12/2025 17:15:00 to Central Coach Station, Mannheim (Germany) arriving at 27/12/2025 01:05:00. 50 Economy ticket for £52 per person are available. Travel duration is 7h 50m
FlixBus	7h 40m	07:55	Prague	Na Knížecí Station	15:35	Mannheim	Central Coach Station	Economy	£52	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 26/12/2025 07:55:00 to Central Coach Station, Mannheim (Germany) arriving at 26/12/2025 15:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 7h 40m
FlixBus	7h 20m	17:45	Prague	Na Knížecí Station	01:05	Mannheim	Central Coach Station	Economy	£52	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 26/12/2025 17:45:00 to Central Coach Station, Mannheim (Germany) arriving at 27/12/2025 01:05:00. 50 Economy ticket for £52 per person are available. Travel duration is 7h 20m
FlixBus	6h 45m	20:15	Prague	ÚAN Florenc	03:00	Mannheim	Central Coach Station	Economy	£78	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 26/12/2025 20:15:00 to Central Coach Station, Mannheim (Germany) arriving at 27/12/2025 03:00:00. 50 Economy ticket for £78 per person are available. Travel duration is 6h 45m

Best Price Offer: The price for the cheapest coach from Prague to Mannheim is £27 on 17/12/2025. Flexible travellers save on ticket prices.

Frequency of bus connections between Prague and Mannheim

See here how frequent the connections between Prague and Mannheim are, during different times and days of the week.

Wednesday is the busiest day, with more than 6 daily coaches from Prague to Mannheim. Sunday has instead the fewest connections, with only 4 daily coaches between Prague and Mannheim.

The busiest time of the day is the Afternoon, with 6 coaches from Prague to Mannheim, while Morning sees the fewest connections between Prague and Mannheim, with 4 offers.

Facts about coaches from Prague to Mannheim

Compare all providers like FlixBus that travel 5 times every day by bus from Prague to Mannheim in one click! Book your bus ticket from Prague to Mannheim starting from £27!

Cheapest Bus	£27
Fastest Bus	6h 20m
Earliest Coach	17:15
Latest Coach	20:40
Daily Bus Connections	5 Ø
Distance	433.6 km
Coach Companies	FlixBus

Cheapest coach connections from Prague to Mannheim

Every day, 5 buses from 1 coach companies leave Prague for Mannheim: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 21/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

Friday 19/12

Saturday 20/12

Sunday 21/12

£57

Monday 22/12

Tuesday 23/12

Wednesday 24/12

£50

Thursday 25/12

Friday 26/12

£52

Saturday 27/12

Sunday 28/12

£58

Monday 29/12

£56

Tuesday 30/12

Wednesday 31/12

Thursday 01/01

Friday 02/01

Saturday 03/01

£54

Sunday 04/01

£56

Monday 05/01

Tuesday 06/01

Wednesday 07/01

Thursday 08/01

Friday 09/01

Saturday 10/01

Sunday 11/01

The cheapest time to travel from Prague to Mannheim

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Mannheim, for the next 30 days.

With a price starting from £25, Friday is the cheapest day for a coach from Prague to Mannheim. Sunday instead is the most expensive day with prices starting from £56.

Afternoon is the cheapest day time for bus tickets from Prague to Mannheim, with £50. Morning is the most expensive time of the day with prices starting from £52.

How to save money travelling from Prague to Mannheim

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Mannheim in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Mannheim, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Mannheim are also emptier.

All bus stations and stops in Prague and Mannheim

The map below shows you where to find all the bus stations in Prague and Mannheim.

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Coach Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Černý Most

Bryksova

Central Coach Station

Heinrich-von-Stephan-Str 6-8

Theresienkrankenhaus

Central Station

Kaiserring

Friedrichsfeld Süd Train Station

Boveristraße Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Mannheim? Compare all modes of transports from Prague to Mannheim.

Service and Comfort on the bus from Prague to Mannheim

Want to know which seat classes are available on the coaches from Prague to Mannheim? Or which bus companies serve the route Prague to Mannheim? Below you will find answers to your questions.

FAQs about the Prague to Mannheim bus

How much does a Prague - Mannheim coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Prague - Mannheim bus trip is available from £27 and takes 7h 50m. Compare offers and save money!

How much could I save by comparing buses from Prague to Mannheim?

The connection Prague to Mannheim is offered by 1 companies with ticket prices ranging from £27 to £78. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Prague - Mannheim route on average every day?

Each day, the bus route from Prague to Mannheim is offered by roughly 5 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Mannheim from Prague take?

The quickest coach from Prague to Mannheim is provided by FlixBus and takes 6h 20m. Coach tickets for this connection cost £63. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Prague to Mannheim?

The earliest bus to Mannheim departs from Prague at 17:15. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Prague to Mannheim?

The latest bus to Mannheim departs from Prague at 20:40. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Prague - Mannheim route?

Passengers looking to travel from Prague to Mannheim can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Prague and Mannheim?

You can check all the direct connections between Prague and Mannheim by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Mannheim from Prague?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Prague Mannheim bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Mannheim bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Mannheim on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Mannheim?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Prague and Mannheim. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Mannheim?

Prices and availability for 5 trips between Prague and Mannheim change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Mannheim

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Mannheim

Here’s an overview of the most popular bus routes to Prague and to Mannheim. Simply click on the connection of your choice, and you will find all the details about your bus route!