Bus tickets Prague to Rome from £42

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Which bus from Prague to Rome is the best?

Check the bus schedule for Prague to Rome. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or RegioJet. To see the full timetable for all coaches just use or search and compare.

today
from £42
tomorrow
from £66
Wednesday
from £63
Thursday
from £62
Friday
from £57
Saturday
from £56
Sunday
from £62

Cheapest bus trips today

Prices are for one way and one person
  • RegioJet
    20h 15m
    0
    18:30
    Prague
    ÚAN Florenc
    14:45
    Rome
    Tiburtina Bus Station
    0
    RegioJet
    Economy
    £42
  • FlixBus
    23h 10m
    0
    23:50
    Prague
    Wilsonova Coach Station
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £59
  • FlixBus
    23h 25m
    0
    23:35
    Prague
    ÚAN Florenc
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £59
  • FlixBus
    19h 15m
    0
    14:15
    Prague
    Wilsonova Coach Station
    09:30
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £62
  • Did you know that if you travel from Prague to Rome via Trieste, you can save more than £8? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      22:20
      Prague
      Roztyly
      09:15
      Trieste
      Central Station
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 50m
    • Distribusion
      9h 35m
      0
      10:05
      Trieste
      Central Bus Station
      19:40
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      £6
    Travel time is 2h 5m longer, but you will save £8

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    25h 5m
    0
    09:40
    Prague
    Na Knížecí Station
    10:45
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £66
  • FlixBus
    27h 35m
    0
    14:30
    Prague
    Černý Most
    18:05
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £67
  • FlixBus
    24h 50m
    0
    17:15
    Prague
    Wilsonova Coach Station
    18:05
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £67
  • FlixBus
    24h 20m
    0
    17:45
    Prague
    Na Knížecí Station
    18:05
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £67
  • FlixBus
    20h 25m
    0
    13:05
    Prague
    Wilsonova Coach Station
    09:30
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £68
  • Did you know that if you travel from Prague to Rome via Trieste, you can save more than £32? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      22:20
      Prague
      Roztyly
      09:15
      Trieste
      Central Station
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 50m
    • Distribusion
      9h 35m
      0
      10:05
      Trieste
      Central Bus Station
      19:40
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      £6
    Travel time is 0h 55m longer, but you will save £32

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    27h 5m
    0
    11:00
    Prague
    Roztyly
    14:05
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £63
  • FlixBus
    23h 20m
    0
    19:25
    Prague
    Zličín
    18:45
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £70
  • FlixBus
    25h 5m
    0
    09:40
    Prague
    Na Knížecí Station
    10:45
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £81
  • FlixBus
    22h 15m
    0
    21:55
    Prague
    ÚAN Florenc
    20:10
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £82
  • FlixBus
    21h 50m
    0
    22:20
    Prague
    Roztyly
    20:10
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £82
  • Did you know that if you travel from Prague to Rome via Trieste, you can save more than £29? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      22:20
      Prague
      Roztyly
      09:15
      Trieste
      Central Station
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 50m
    • Distribusion
      9h 35m
      0
      10:05
      Trieste
      Central Bus Station
      19:40
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      £6
    Travel Time is 0h 30m shorter, and you will save £29

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    25h 20m
    0
    20:15
    Prague
    Wilsonova Coach Station
    21:35
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £62
  • FlixBus
    22h 45m
    0
    14:30
    Prague
    Černý Most
    13:15
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £68
  • FlixBus
    20h 0m
    0
    17:15
    Prague
    ÚAN Florenc
    13:15
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £68
  • FlixBus
    19h 30m
    0
    17:45
    Prague
    Na Knížecí Station
    13:15
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £68
  • FlixBus
    21h 20m
    0
    17:45
    Prague
    Na Knížecí Station
    15:05
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £68
  • Did you know that if you travel from Prague to Rome via Trieste, you can save more than £28? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      22:20
      Prague
      Roztyly
      09:15
      Trieste
      Central Station
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 50m
    • Distribusion
      9h 35m
      0
      10:05
      Trieste
      Central Bus Station
      19:40
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      £6
    Travel time is 1h 50m longer, but you will save £28

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    23h 10m
    0
    23:50
    Prague
    Wilsonova Coach Station
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £57
  • FlixBus
    23h 25m
    0
    23:35
    Prague
    ÚAN Florenc
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £57
  • FlixBus
    24h 45m
    0
    22:15
    Prague
    Na Knížecí Station
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £58
  • FlixBus
    25h 20m
    0
    20:15
    Prague
    Wilsonova Coach Station
    21:35
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £63
  • FlixBus
    20h 35m
    0
    21:25
    Prague
    ÚAN Florenc
    18:00
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £65
  • Did you know that if you travel from Prague to Rome via Trieste, you can save more than £23? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      22:20
      Prague
      Roztyly
      09:15
      Trieste
      Central Station
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 50m
    • Distribusion
      9h 35m
      0
      10:05
      Trieste
      Central Bus Station
      19:40
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      £6
    Travel time is 0h 45m longer, but you will save £23

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    23h 25m
    0
    12:50
    Prague
    ÚAN Florenc
    12:15
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £56
  • FlixBus
    23h 10m
    0
    13:05
    Prague
    Wilsonova Coach Station
    12:15
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £56
  • FlixBus
    20h 30m
    0
    02:30
    Prague
    Wilsonova Coach Station
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £57
  • FlixBus
    19h 50m
    0
    11:00
    Prague
    ÚAN Florenc
    06:50
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £57
  • FlixBus
    19h 35m
    0
    11:15
    Prague
    Wilsonova Coach Station
    06:50
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    £57
  • Did you know that if you travel from Prague to Rome via Trieste, you can save more than £22? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      22:20
      Prague
      Roztyly
      09:15
      Trieste
      Central Station
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 50m
    • Distribusion
      9h 35m
      0
      10:05
      Trieste
      Central Bus Station
      19:40
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      £6
    Travel time is 1h 45m longer, but you will save £22

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    23h 10m
    0
    23:50
    Prague
    Wilsonova Coach Station
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £62
  • FlixBus
    23h 25m
    0
    23:35
    Prague
    ÚAN Florenc
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £62
  • FlixBus
    24h 45m
    0
    22:15
    Prague
    Na Knížecí Station
    23:00
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £68
  • FlixBus
    20h 0m
    0
    21:25
    Prague
    ÚAN Florenc
    17:25
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £69
  • FlixBus
    25h 30m
    0
    11:45
    Prague
    Wilsonova Coach Station
    13:15
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    £70
  • Did you know that if you travel from Prague to Rome via Trieste, you can save more than £28? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      22:20
      Prague
      Roztyly
      09:15
      Trieste
      Central Station
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 50m
    • Distribusion
      9h 35m
      0
      10:05
      Trieste
      Central Bus Station
      19:40
      Rome
      Tiburtina Bus Station
      0
      Distribusion
      Premium Economy
      £6
    Travel time is 1h 20m longer, but you will save £28

What is the best day and time to travel by bus between Prague and Rome?

Here is the frequency of all coach connections from Prague to Rome. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Saturday is the busiest day, with more than 40 daily coaches from Prague to Rome. Wednesday has instead the fewest connections, with only 20 daily coaches between Prague and Rome.
The busiest time of the day is the Afternoon, with 98 coaches from Prague to Rome, while Night sees the fewest connections between Prague and Rome, with 14 offers.

All facts for Prague to Rome bus at a glance

Compare all coach operators like FlixBus and RegioJet that travel daily 32 times by bus from Prague to Rome in one click. Book your Prague to Rome bus ticket starting from £42!

Cheapest Bus £42
Fastest Bus 19h 15m
Earliest Coach 02:30
Latest Coach 23:50
Daily Bus Connections 32 Ø
Distance 921.0 km
Coach Companies FlixBus and RegioJet

What are the cheapest coach tickets from Prague to Rome?

Every day, 32 buses from 2 coach companies leave Prague for Rome. Check the table below to find the cheapest prices for coach tickets for this route, starting from 31/03/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 31/03
£59
Tuesday 01/04
£66
Wednesday 02/04
£63
Thursday 03/04
£62
Friday 04/04
£57
Saturday 05/04
£56
Sunday 06/04
£62
Monday 07/04
£46
Tuesday 08/04
£49
Wednesday 09/04
£58
Thursday 10/04
£62
Friday 11/04
£76
Saturday 12/04
£70
Sunday 13/04
£64
Monday 14/04
£49
Tuesday 15/04
£52
Wednesday 16/04
£61
Thursday 17/04
£94
Friday 18/04
£70
Saturday 19/04
£61
Sunday 20/04
£76
Monday 21/04
£69
Tuesday 22/04
£59
Wednesday 23/04
£67
Thursday 24/04
£70
Friday 25/04
£63
Saturday 26/04
£60
Sunday 27/04

The cheapest time to travel from Prague to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Rome, for the next 30 days.
With a price starting from £42, Monday is the cheapest day for a coach from Prague to Rome. Tuesday instead is the most expensive day with prices starting from £66.
Evening is the cheapest day time for bus tickets from Prague to Rome, with £42. Morning is the most expensive time of the day with prices starting from £57.

How to save money travelling from Prague to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Prague to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Prague to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Rome are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Prague and Rome

Here is a map with all coach stations in Prague and Rome. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Rome? Compare all modes of transports from Prague to Rome.

All you need to know when you travel by bus from Prague to Rome

Check all information on comfort and services on the coaches from Prague to Rome. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Prague to Rome bus

How much does a Prague Rome coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Prague Rome bus trip is available from £42 and takes 20h 15m. Compare offers and save money!

How much could I save by comparing buses from Prague to Rome?

This connection is offered by 2 companies with ticket prices ranging from £42 to £117. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Rome.

How many connections are available for the Prague Rome route on average every day?

Each day, the bus route from Prague to Rome is offered by roughly 32 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Rome from Prague take?

The quickest coach from Prague to Rome is provided by FlixBus and takes 19h 15m. Coach tickets for this connection cost £62. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Prague to Rome?

The earliest bus to Rome departs from Prague at 02:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Prague to Rome?

The latest bus to Rome departs from Prague at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Prague Rome route?

Passengers looking to travel from Prague to Rome can travel with FlixBus and RegioJet. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Prague and Rome?

You can check all the direct connections between Prague and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the bus to Rome from Prague?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Prague Rome bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Rome on your planned travel date.

Available seat classes which are offered on the bus route Prague to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Rome

Here’s an overview of the most popular bus routes to Prague and to Rome. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Florence to Prague bus Florence to Prague bus
Bus from Česká Lípa to Prague Bus from Česká Lípa to Prague
Bus to Prague from Brussels Bus to Prague from Brussels
Coach to Prague from Vinnytsia Coach to Prague from Vinnytsia
Potenza to Rome bus Potenza to Rome bus
Coach from Lyon to Rome Coach from Lyon to Rome
Bus to Rome from Taranto Bus to Rome from Taranto
Bus to Rome from Civitanova Bus to Rome from Civitanova
Popular Airport Transfers to Prague and to Rome
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