Bus and Coach from Rome to Prague: Compare all prices

Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus for the next days.

today

£80

tomorrow

£73

Monday

£69

Tuesday

£61

Wednesday

£66

Thursday

£73

Friday

£83

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 5m	22:55	Rome	Tiburtina Bus Station	03:00	Prague	Wilsonova Coach Station	Economy	£80	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 13/12/2025 22:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 15/12/2025 03:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 28h 5m
FlixBus	24h 0m	22:55	Rome	Tiburtina Bus Station	22:55	Prague	Na Knížecí Station	Economy	£80	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 13/12/2025 22:55:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 14/12/2025 22:55:00. 50 Economy ticket for £80 per person are available. Travel duration is 24h 0m
FlixBus	20h 45m	21:00	Rome	Tiburtina Bus Station	17:45	Prague	ÚAN Florenc	Economy	£81	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 13/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 14/12/2025 17:45:00. 50 Economy ticket for £81 per person are available. Travel duration is 20h 45m
FlixBus	20h 35m	22:55	Rome	Tiburtina Bus Station	19:30	Prague	ÚAN Florenc	Economy	£81	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 13/12/2025 22:55:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 14/12/2025 19:30:00. 50 Economy ticket for £81 per person are available. Travel duration is 20h 35m
FlixBus	20h 30m	21:00	Rome	Tiburtina Bus Station	17:30	Prague	Wilsonova Coach Station	Economy	£81	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 13/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 14/12/2025 17:30:00. 50 Economy ticket for £81 per person are available. Travel duration is 20h 30m

Did you know that if you travel from Rome to Prague via Udine, you can save more than £8? You can find the corresponding connections below.
- FlixBus
  
  24h 25m
  
  0
  
  13:05
  
  Rome
  Anagnina Bus Station
  
  23:40
  
  Udine
  Train Station
  
  0
  
  Economy
  
  £29
  
  A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 15/12/2025 13:05:00 to Train Station, Udine (Italy) arriving at 15/12/2025 23:40:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 35m
- FlixBus
  
  13h 45m
  
  0
  
  23:45
  
  Udine
  Train Station
  
  13:30
  
  Prague
  Roztyly
  
  0
  
  Economy
  
  £42
  
  A Bus from FlixBus goes from Train Station, Udine (Italy) at 15/12/2025 23:45:00 to Roztyly, Prague (Czech Republic) arriving at 16/12/2025 13:30:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 45m
Travel time is 3h 55m longer, but you will save £8

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	26h 55m	21:00	Rome	Tiburtina Bus Station	23:55	Prague	Wilsonova Coach Station	Economy	£73	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 14/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 15/12/2025 23:55:00. 50 Economy ticket for £73 per person are available. Travel duration is 26h 55m
FlixBus	25h 15m	21:00	Rome	Tiburtina Bus Station	22:15	Prague	Roztyly	Economy	£73	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 14/12/2025 21:00:00 to Roztyly, Prague (Czech Republic) arriving at 15/12/2025 22:15:00. 50 Economy ticket for £73 per person are available. Travel duration is 25h 15m
FlixBus	20h 30m	21:00	Rome	Tiburtina Bus Station	17:30	Prague	Wilsonova Coach Station	Economy	£74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 14/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 15/12/2025 17:30:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 30m
FlixBus	20h 45m	21:00	Rome	Tiburtina Bus Station	17:45	Prague	ÚAN Florenc	Economy	£74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 14/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 15/12/2025 17:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 45m
FlixBus	23h 20m	21:00	Rome	Tiburtina Bus Station	20:20	Prague	Na Knížecí Station	Economy	£74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 14/12/2025 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 15/12/2025 20:20:00. 50 Economy ticket for £74 per person are available. Travel duration is 23h 20m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 0m	17:00	Rome	Tiburtina Bus Station	20:00	Prague	Wilsonova Coach Station	Economy	£69	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/12/2025 17:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/12/2025 20:00:00. 50 Economy ticket for £69 per person are available. Travel duration is 27h 0m
FlixBus	26h 45m	17:00	Rome	Tiburtina Bus Station	19:45	Prague	Na Knížecí Station	Economy	£69	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/12/2025 17:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 16/12/2025 19:45:00. 50 Economy ticket for £69 per person are available. Travel duration is 26h 45m
FlixBus	24h 25m	13:05	Rome	Anagnina Bus Station	13:30	Prague	Roztyly	Economy	£69	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 15/12/2025 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 16/12/2025 13:30:00. 50 Economy ticket for £69 per person are available. Travel duration is 24h 25m
FlixBus	20h 45m	09:30	Rome	Tiburtina Bus Station	06:15	Prague	ÚAN Florenc	Economy	£70	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/12/2025 09:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/12/2025 06:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 45m
FlixBus	20h 30m	09:30	Rome	Tiburtina Bus Station	06:00	Prague	Wilsonova Coach Station	Economy	£70	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 15/12/2025 09:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/12/2025 06:00:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 30m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 30m	21:00	Rome	Tiburtina Bus Station	17:30	Prague	Wilsonova Coach Station	Economy	£61	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 17/12/2025 17:30:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 30m
FlixBus	20h 45m	21:00	Rome	Tiburtina Bus Station	17:45	Prague	ÚAN Florenc	Economy	£61	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/12/2025 17:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 20h 45m
FlixBus	24h 35m	17:00	Rome	Tiburtina Bus Station	17:35	Prague	Hradčanská	Economy	£61	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/12/2025 17:00:00 to Hradčanská, Prague (Czech Republic) arriving at 17/12/2025 17:35:00. 50 Economy ticket for £61 per person are available. Travel duration is 24h 35m
FlixBus	26h 55m	21:00	Rome	Tiburtina Bus Station	23:55	Prague	Wilsonova Coach Station	Economy	£62	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 17/12/2025 23:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 26h 55m
FlixBus	23h 20m	21:00	Rome	Tiburtina Bus Station	20:20	Prague	Na Knížecí Station	Economy	£62	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 16/12/2025 21:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/12/2025 20:20:00. 50 Economy ticket for £62 per person are available. Travel duration is 23h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 25m	23:50	Rome	Tiburtina Bus Station	03:15	Prague	Wilsonova Coach Station	Economy	£66	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/12/2025 23:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 03:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 25m
FlixBus	26h 15m	09:30	Rome	Tiburtina Bus Station	11:45	Prague	Na Knížecí Station	Economy	£67	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/12/2025 09:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 18/12/2025 11:45:00. 50 Economy ticket for £67 per person are available. Travel duration is 26h 15m
FlixBus	26h 10m	17:00	Rome	Tiburtina Bus Station	19:10	Prague	Na Knížecí Station	Economy	£67	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 17/12/2025 17:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 18/12/2025 19:10:00. 50 Economy ticket for £67 per person are available. Travel duration is 26h 10m
FlixBus	27h 40m	23:35	Rome	Anagnina Bus Station	03:15	Prague	Wilsonova Coach Station	Economy	£67	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 17/12/2025 23:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 03:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 27h 40m
FlixBus	24h 5m	13:05	Rome	Anagnina Bus Station	13:10	Prague	ÚAN Florenc	Economy	£67	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 17/12/2025 13:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 13:10:00. 50 Economy ticket for £67 per person are available. Travel duration is 24h 5m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 5m	13:05	Rome	Anagnina Bus Station	12:10	Prague	Wilsonova Coach Station	Economy	£73	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 18/12/2025 13:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 12:10:00. 50 Economy ticket for £73 per person are available. Travel duration is 23h 5m
FlixBus	20h 45m	21:00	Rome	Tiburtina Bus Station	17:45	Prague	ÚAN Florenc	Economy	£74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 17:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 45m
FlixBus	20h 30m	21:00	Rome	Tiburtina Bus Station	17:30	Prague	Wilsonova Coach Station	Economy	£74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 17:30:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 30m
FlixBus	20h 20m	13:05	Rome	Anagnina Bus Station	09:25	Prague	ÚAN Florenc	Economy	£74	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 18/12/2025 13:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 09:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 20m
FlixBus	24h 45m	12:45	Rome	Anagnina Bus Station	13:30	Prague	Roztyly	Economy	£75	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 18/12/2025 12:45:00 to Roztyly, Prague (Czech Republic) arriving at 19/12/2025 13:30:00. 50 Economy ticket for £75 per person are available. Travel duration is 24h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 30m	21:00	Rome	Tiburtina Bus Station	17:30	Prague	Wilsonova Coach Station	Economy	£83	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 21:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 17:30:00. 50 Economy ticket for £83 per person are available. Travel duration is 20h 30m
FlixBus	24h 50m	17:00	Rome	Tiburtina Bus Station	17:50	Prague	Na Knížecí Station	Economy	£83	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 17:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 20/12/2025 17:50:00. 50 Economy ticket for £83 per person are available. Travel duration is 24h 50m
FlixBus	20h 45m	21:00	Rome	Tiburtina Bus Station	17:45	Prague	ÚAN Florenc	Economy	£83	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 21:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/12/2025 17:45:00. 50 Economy ticket for £83 per person are available. Travel duration is 20h 45m
FlixBus	24h 20m	17:25	Rome	Anagnina Bus Station	17:45	Prague	ÚAN Florenc	Economy	£83	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 19/12/2025 17:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/12/2025 17:45:00. 50 Economy ticket for £83 per person are available. Travel duration is 24h 20m
FlixBus	24h 25m	13:05	Rome	Anagnina Bus Station	13:30	Prague	Roztyly	Economy	£84	A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 19/12/2025 13:05:00 to Roztyly, Prague (Czech Republic) arriving at 20/12/2025 13:30:00. 50 Economy ticket for £84 per person are available. Travel duration is 24h 25m

Did you know that if you travel from Rome to Prague via Udine, you can save more than £11? You can find the corresponding connections below.
- FlixBus
  
  24h 25m
  
  0
  
  13:05
  
  Rome
  Anagnina Bus Station
  
  23:40
  
  Udine
  Train Station
  
  0
  
  Economy
  
  £29
  
  A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 15/12/2025 13:05:00 to Train Station, Udine (Italy) arriving at 15/12/2025 23:40:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 35m
- FlixBus
  
  13h 45m
  
  0
  
  23:45
  
  Udine
  Train Station
  
  13:30
  
  Prague
  Roztyly
  
  0
  
  Economy
  
  £42
  
  A Bus from FlixBus goes from Train Station, Udine (Italy) at 15/12/2025 23:45:00 to Roztyly, Prague (Czech Republic) arriving at 16/12/2025 13:30:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 45m
Travel time is 3h 55m longer, but you will save £11

Best Price Offer: The price for the cheapest coach from Rome to Prague is £61 on 16/12/2025. Flexible travellers save on ticket prices.

Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.

Saturday is the busiest day, with more than 45 daily coaches from Rome to Prague. Tuesday has instead the fewest connections, with only 25 daily coaches between Rome and Prague.

The busiest time of the day is the Afternoon, with 123 coaches from Rome to Prague, while Night sees the fewest connections between Rome and Prague, with 4 offers.

Facts about coaches from Rome to Prague

Compare all providers like FlixBus that travel 37 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from £61!

Cheapest Bus	£61
Fastest Bus	20h 20m
Earliest Coach	07:30
Latest Coach	23:50
Daily Bus Connections	37 Ø
Distance	921.0 km
Coach Companies	FlixBus

Cheapest coach connections from Rome to Prague

Every day, 37 buses from 1 coach companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 13/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 08/12

Tuesday 09/12

Wednesday 10/12

Thursday 11/12

Friday 12/12

Saturday 13/12

£80

Sunday 14/12

£73

Monday 15/12

£69

Tuesday 16/12

£61

Wednesday 17/12

£66

Thursday 18/12

£73

Friday 19/12

£83

Saturday 20/12

£89

Sunday 21/12

£97

Monday 22/12

£84

Tuesday 23/12

£88

Wednesday 24/12

£89

Thursday 25/12

£89

Friday 26/12

£97

Saturday 27/12

£97

Sunday 28/12

£103

Monday 29/12

£99

Tuesday 30/12

£99

Wednesday 31/12

£90

Thursday 01/01

£114

Friday 02/01

£110

Saturday 03/01

£96

Sunday 04/01

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.

With a price starting from £58, Thursday is the cheapest day for a coach from Rome to Prague. Friday instead is the most expensive day with prices starting from £83.

Night is the cheapest day time for bus tickets from Rome to Prague, with £58. Morning is the most expensive time of the day with prices starting from £63.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Prague are also emptier.

All bus stations and stops in Rome and Prague

The map below shows you where to find all the bus stations in Rome and Prague.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Largo Guido Mazzoni 4

Tiburtina Coach Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Coach Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Hradčanská

Milady Horákové 115/107

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Prague? Compare all modes of transports from Rome to Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the coaches from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome - Prague coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Prague bus trip is available from £61 and takes 20h 30m. Compare offers and save money!

How much could I save by comparing buses from Rome to Prague?

The connection Rome to Prague is offered by 1 companies with ticket prices ranging from £61 to £141. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Prague route on average every day?

Each day, the bus route from Rome to Prague is offered by roughly 37 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Prague from Rome take?

The quickest coach from Rome to Prague is provided by FlixBus and takes 20h 20m. Coach tickets for this connection cost £82. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus to Prague departs from Rome at 07:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Prague?

The latest bus to Prague departs from Rome at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Prague route?

Passengers looking to travel from Rome to Prague can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Prague from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Prague bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

Available seat classes which are offered on the bus route Rome to Prague

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!