Which bus from San Antonio, TX to San Diego is the best?
Check the bus schedule for San Antonio, TX to San Diego. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound Lines Mexico | 48h 55m | 19:15 | San Antonio, TX | Coach Station | 18:10 | San Diego | Old Town Transit Center | Economy | £124 |
A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 19:15:00 to Old Town Transit Center, San Diego (USA) arriving at 17/12/2025 18:10:00. 50 Economy ticket for £124 per person are available. Travel duration is 48h 55m
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| Greyhound Lines Mexico | 53h 0m | 19:15 | San Antonio, TX | Coach Station | 22:15 | San Diego | Seaport Village | Economy | £124 |
A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 19:15:00 to Seaport Village, San Diego (USA) arriving at 17/12/2025 22:15:00. 50 Economy ticket for £124 per person are available. Travel duration is 53h 0m
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| Greyhound US | 37h 0m | 06:10 | San Antonio, TX | Coach Station | 17:10 | San Diego | San Ysidro Transit Center | Economy | £148 |
A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 16/12/2025 17:10:00. 50 Economy ticket for £148 per person are available. Travel duration is 37h 0m
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| Greyhound US | 42h 5m | 06:10 | San Antonio, TX | Coach Station | 22:15 | San Diego | Seaport Village | Economy | £148 |
A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to Seaport Village, San Diego (USA) arriving at 16/12/2025 22:15:00. 50 Economy ticket for £148 per person are available. Travel duration is 42h 5m
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| FlixBus | 43h 35m | 18:10 | San Antonio, TX | Coach Station | 11:45 | San Diego | Old Town Transit Center | Economy | £148 |
A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 18:10:00 to Old Town Transit Center, San Diego (USA) arriving at 17/12/2025 11:45:00. 50 Economy ticket for £148 per person are available. Travel duration is 43h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound Lines Mexico | 43h 15m | 01:30 | San Antonio, TX | Coach Station | 18:45 | San Diego | San Ysidro Transit Center | Economy | £159 |
A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 01:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/12/2025 18:45:00. 50 Economy ticket for £159 per person are available. Travel duration is 43h 15m
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| FlixBus | 44h 10m | 18:10 | San Antonio, TX | Coach Station | 12:20 | San Diego | San Ysidro Transit Center | Economy | £164 |
A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 18:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 12:20:00. 50 Economy ticket for £164 per person are available. Travel duration is 44h 10m
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| Greyhound Lines Mexico | 42h 40m | 06:05 | San Antonio, TX | Coach Station | 22:45 | San Diego | San Ysidro Transit Center | Economy | £172 |
A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 06:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/12/2025 22:45:00. 50 Economy ticket for £172 per person are available. Travel duration is 42h 40m
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| Greyhound Lines Mexico | 49h 30m | 19:15 | San Antonio, TX | Coach Station | 18:45 | San Diego | San Ysidro Transit Center | Economy | £186 |
A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 19:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 18:45:00. 50 Economy ticket for £186 per person are available. Travel duration is 49h 30m
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| FlixBus | 46h 0m | 18:10 | San Antonio, TX | Coach Station | 14:10 | San Diego | Old Town Transit Center | Economy | £190 |
A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 18:10:00 to Old Town Transit Center, San Diego (USA) arriving at 18/12/2025 14:10:00. 50 Economy ticket for £190 per person are available. Travel duration is 46h 0m
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Busbud41h 35m006:10San Antonio, TXCoach Station15:35El Paso, TXCoach Station0EconomyA Bus from Busbud goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to Coach Station, El Paso, TX (USA) arriving at 15/12/2025 15:35:00. 50 Economy ticket for £58 per person are available. Travel duration is 10h 25m
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FlixBus20h 45m002:00El Paso, TXCoach Station21:45San DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Coach Station, El Paso, TX (USA) at 16/12/2025 02:00:00 to La Jolla Village, San Diego (USA) arriving at 16/12/2025 21:45:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 45m
Waiting Time 10h 25m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 34h 30m | 06:10 | San Antonio, TX | Coach Station | 14:40 | San Diego | San Ysidro Transit Center | Economy | £180 |
A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 06:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 19/12/2025 14:40:00. 50 Economy ticket for £180 per person are available. Travel duration is 34h 30m
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| FlixBus | 47h 5m | 21:15 | San Antonio, TX | Coach Station | 18:20 | San Diego | San Ysidro Transit Center | Economy | £213 |
A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 21:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 20/12/2025 18:20:00. 50 Economy ticket for £213 per person are available. Travel duration is 47h 5m
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| FlixBus | 42h 25m | 18:10 | San Antonio, TX | Coach Station | 10:35 | San Diego | San Ysidro Transit Center | Economy | £223 |
A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 18:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 20/12/2025 10:35:00. 50 Economy ticket for £223 per person are available. Travel duration is 42h 25m
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Busbud41h 35m006:10San Antonio, TXCoach Station15:35El Paso, TXCoach Station0EconomyA Bus from Busbud goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to Coach Station, El Paso, TX (USA) arriving at 15/12/2025 15:35:00. 50 Economy ticket for £58 per person are available. Travel duration is 10h 25m
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FlixBus20h 45m002:00El Paso, TXCoach Station21:45San DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Coach Station, El Paso, TX (USA) at 16/12/2025 02:00:00 to La Jolla Village, San Diego (USA) arriving at 16/12/2025 21:45:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 45m
Waiting Time 10h 25m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 34h 0m | 06:10 | San Antonio, TX | Coach Station | 14:10 | San Diego | Old Town Transit Center | Economy | £137 |
A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to Old Town Transit Center, San Diego (USA) arriving at 20/12/2025 14:10:00. 50 Economy ticket for £137 per person are available. Travel duration is 34h 0m
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| Greyhound US | 33h 30m | 06:10 | San Antonio, TX | Coach Station | 13:40 | San Diego | La Jolla Village | Economy | £138 |
A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to La Jolla Village, San Diego (USA) arriving at 20/12/2025 13:40:00. 50 Economy ticket for £138 per person are available. Travel duration is 33h 30m
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| Greyhound US | 42h 5m | 06:10 | San Antonio, TX | Coach Station | 22:15 | San Diego | Seaport Village | Economy | £189 |
A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to Seaport Village, San Diego (USA) arriving at 20/12/2025 22:15:00. 50 Economy ticket for £189 per person are available. Travel duration is 42h 5m
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| FlixBus | 51h 0m | 21:15 | San Antonio, TX | Coach Station | 22:15 | San Diego | Seaport Village | Economy | £200 |
A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Seaport Village, San Diego (USA) arriving at 21/12/2025 22:15:00. 50 Economy ticket for £200 per person are available. Travel duration is 51h 0m
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| FlixBus | 46h 30m | 21:15 | San Antonio, TX | Coach Station | 17:45 | San Diego | Old Town Transit Center | Economy | £203 |
A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Old Town Transit Center, San Diego (USA) arriving at 21/12/2025 17:45:00. 50 Economy ticket for £203 per person are available. Travel duration is 46h 30m
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Best Price Offer: The price for the cheapest coach from San Antonio, TX to San Diego is £124 on 15/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between San Antonio, TX and San Diego?
All facts for San Antonio, TX to San Diego bus at a glance
Compare all coach operators like FlixBus, Greyhound Lines Mexico and Greyhound US that travel daily 11 times by bus from San Antonio, TX to San Diego in one click. Book your San Antonio, TX to San Diego bus ticket starting from £124!
| Cheapest Bus | £124 |
| Fastest Bus | 31h 30m |
| Earliest Coach | 01:30 |
| Latest Coach | 21:15 |
| Daily Bus Connections | 11 Ø |
| Distance | 1,812.4 km |
| Coach Companies | FlixBus, Greyhound Lines Mexico and Greyhound US |
What are the cheapest coach tickets from San Antonio, TX to San Diego?
Every day, 11 buses from 3 coach companies leave San Antonio, TX for San Diego. Check the table below to find the cheapest prices for coach tickets for this route, starting from 14/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from San Antonio, TX to San Diego
How to save money travelling from San Antonio, TX to San Diego
Book the ticket from San Antonio, TX to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from San Antonio, TX to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from San Antonio, TX to San Diego are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in San Antonio, TX and San Diego
Here is a map with all coach stations in San Antonio, TX and San Diego. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from San Antonio, TX to San Diego
FAQs for San Antonio, TX to San Diego bus
How much does a San Antonio, TX San Diego coach trip cost?
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How many connections are available for the San Antonio, TX San Diego route on average every day?
How long does a bus to San Diego from San Antonio, TX take?
What time is the first bus from San Antonio, TX to San Diego?
What time is the last coach from San Antonio, TX to San Diego?
Which bus companies serve the San Antonio, TX San Diego route?
Is there a direct bus between San Antonio, TX and San Diego?
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Available seat classes which are offered on the bus route San Antonio, TX to San Diego
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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