Bus tickets Santiago, RM to La Serena from £6

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Compare all timetables for the bus from Santiago, RM to La Serena

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to La Serena from various bus operators like Turbus, Cikbus Elité or FlixBus for the next days.
today
from £6
tomorrow
from £6
Sunday
from £6
Monday
from £6
Tuesday
from £6
Wednesday
from £6
Thursday
from £6

Cheapest bus trips today

Prices are for one way and one person
  • Pluss Chile
    6h 30m
    0
    07:45
    Santiago, RM
    Sur Bus Station
    14:15
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    £6
  • Cikbus Elité
    6h 0m
    0
    23:00
    Santiago, RM
    Sur Bus Station
    05:00
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    £6
  • Buses Romani
    6h 30m
    0
    10:30
    Santiago, RM
    Sur Bus Station
    17:00
    La Serena
    Bus Station
    0
    Buses Romani
    Premium Economy
    £6
  • FlixBus
    6h 10m
    0
    13:15
    Santiago, RM
    Terminal San Borja
    19:25
    La Serena
    Bus Station
    0
    FlixBus
    Premium Economy
    £9
  • Turbus
    7h 0m
    0
    14:30
    Santiago, RM
    Terminal San Borja
    21:30
    La Serena
    Bus Station
    0
    Turbus
    Premium Economy
    £10

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Pluss Chile
    6h 30m
    0
    07:45
    Santiago, RM
    Sur Bus Station
    14:15
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    £6
  • Cikbus Elité
    7h 15m
    0
    08:00
    Santiago, RM
    Terminal San Borja
    15:15
    La Serena
    Bus Stop
    0
    Cikbus Elité
    Business
    £7
  • FlixBus
    6h 10m
    0
    10:15
    Santiago, RM
    Terminal San Borja
    16:25
    La Serena
    Bus Station
    0
    FlixBus
    Premium Economy
    £9
  • Turbus
    7h 0m
    0
    14:30
    Santiago, RM
    Terminal San Borja
    21:30
    La Serena
    Bus Station
    0
    Turbus
    Premium Economy
    £10
  • Serena Mar
    7h 0m
    0
    10:00
    Santiago, RM
    Terminal San Borja
    17:00
    La Serena
    Bus Station
    0
    Serena Mar
    First Class
    £10

Cheapest bus trips Sunday

Prices are for one way and one person
  • Cikbus Elité
    7h 15m
    0
    08:00
    Santiago, RM
    Sur Bus Station
    15:15
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    £6
  • Pluss Chile
    6h 30m
    0
    07:45
    Santiago, RM
    Sur Bus Station
    14:15
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    £6
  • Buses Romani
    6h 30m
    0
    10:30
    Santiago, RM
    Sur Bus Station
    17:00
    La Serena
    Bus Station
    0
    Buses Romani
    Premium Economy
    £6
  • FlixBus
    6h 5m
    0
    06:15
    Santiago, RM
    Terminal San Borja
    12:20
    La Serena
    Bus Station
    0
    FlixBus
    Premium Economy
    £9
  • Turbus
    7h 0m
    0
    14:30
    Santiago, RM
    Terminal San Borja
    21:30
    La Serena
    Bus Station
    0
    Turbus
    Premium Economy
    £10

Cheapest bus trips Monday

Prices are for one way and one person
  • Pluss Chile
    6h 30m
    0
    07:45
    Santiago, RM
    Sur Bus Station
    14:15
    La Serena
    Bus Station
    0
    Pluss Chile
    Premium Economy
    £6
  • Cikbus Elité
    7h 10m
    0
    13:30
    Santiago, RM
    Sur Bus Station
    20:40
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    £6
  • Buses Romani
    6h 30m
    0
    10:30
    Santiago, RM
    Sur Bus Station
    17:00
    La Serena
    Bus Station
    0
    Buses Romani
    Premium Economy
    £6
  • FlixBus
    6h 10m
    0
    06:15
    Santiago, RM
    Terminal San Borja
    12:25
    La Serena
    Bus Station
    0
    FlixBus
    Premium Economy
    £8
  • Turbus
    7h 0m
    0
    14:30
    Santiago, RM
    Terminal San Borja
    21:30
    La Serena
    Bus Station
    0
    Turbus
    Premium Economy
    £10

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Turbus
    7h 10m
    0
    06:55
    Santiago, RM
    Terminal Alameda
    14:05
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    £6
  • FlixBus
    6h 10m
    0
    10:15
    Santiago, RM
    Terminal San Borja
    16:25
    La Serena
    Bus Station
    0
    FlixBus
    Premium Economy
    £6
  • Buses Romani
    6h 30m
    0
    10:30
    Santiago, RM
    Sur Bus Station
    17:00
    La Serena
    Bus Station
    0
    Buses Romani
    Premium Economy
    £6
  • Condor Bus
    6h 50m
    0
    14:30
    Santiago, RM
    Sur Bus Station
    21:20
    La Serena
    Bus Station
    0
    Condor Bus
    Premium Economy
    £6
  • Cikbus Elité
    6h 15m
    0
    09:30
    Santiago, RM
    Sur Bus Station
    15:45
    La Serena
    Bus Station
    0
    Cikbus Elité
    Premium Economy
    £8

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Turbus
    6h 20m
    0
    06:10
    Santiago, RM
    Terminal Alameda
    12:30
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    £6
  • FlixBus
    6h 10m
    0
    10:15
    Santiago, RM
    Terminal San Borja
    16:25
    La Serena
    Bus Station
    0
    FlixBus
    Premium Economy
    £6
  • Condor Bus
    7h 0m
    0
    14:30
    Santiago, RM
    Sur Bus Station
    21:30
    La Serena
    Bus Station
    0
    Condor Bus
    Premium Economy
    £6
  • Cormar Bus
    6h 10m
    0
    22:50
    Santiago, RM
    Terminal San Borja
    05:00
    La Serena
    Bus Station
    0
    Cormar Bus
    First Class
    £11
  • Pullman San Andres
    7h 0m
    0
    14:00
    Santiago, RM
    Terminal San Borja
    21:00
    La Serena
    Bus Station
    0
    Pullman San Andres
    First Class
    £12

Cheapest bus trips Thursday

Prices are for one way and one person
  • Turbus
    6h 20m
    0
    06:10
    Santiago, RM
    Terminal Alameda
    12:30
    La Serena
    Bus Stop
    0
    Turbus
    Premium Economy
    £6
  • FlixBus
    6h 10m
    0
    10:15
    Santiago, RM
    Terminal San Borja
    16:25
    La Serena
    Bus Station
    0
    FlixBus
    Economy
    £6
  • Buses Romani
    6h 30m
    0
    10:30
    Santiago, RM
    Sur Bus Station
    17:00
    La Serena
    Bus Station
    0
    Buses Romani
    Premium Economy
    £6
  • Condor Bus
    6h 35m
    0
    18:00
    Santiago, RM
    Sur Bus Station
    00:35
    La Serena
    Bus Station
    0
    Condor Bus
    Premium Economy
    £6
  • Cikbus Elité
    7h 15m
    0
    08:00
    Santiago, RM
    Terminal San Borja
    15:15
    La Serena
    Bus Stop
    0
    Cikbus Elité
    Business
    £7

Frequency of bus connections between Santiago, RM and La Serena

See here how frequent the connections between Santiago, RM and La Serena are, during different times and days of the week.
Sunday is the busiest day, with more than 323 daily coaches from Santiago, RM to La Serena. Wednesday has instead the fewest connections, with only 118 daily coaches between Santiago, RM and La Serena.
The busiest time of the day is the Evening, with 672 coaches from Santiago, RM to La Serena, while Night sees the fewest connections between Santiago, RM and La Serena, with 14 offers.

Facts about coaches from Santiago, RM to La Serena

Compare all providers like Turbus, Cikbus Elité and FlixBus that travel 236 times every day by bus from Santiago, RM to La Serena in one click! Book your bus ticket from Santiago, RM to La Serena starting from £6!

Cheapest Bus £6
Fastest Bus 5h 20m
Earliest Coach 00:10
Latest Coach 23:59
Daily Bus Connections 236 Ø
Distance 397.3 km
Coach Companies Turbus, Cikbus Elité, FlixBus, Nueva Andimar Vip, Pluss Chile, Pullman San Andres, Condor Bus, Pullman Bus, Cormar Bus, Buses Romani and 4 more.

Cheapest coach connections from Santiago, RM to La Serena

Every day, 236 buses from 14 coach companies leave Santiago, RM for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 28/03/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 24/03
Tuesday 25/03
Wednesday 26/03
Thursday 27/03
Friday 28/03
£6
Saturday 29/03
£6
Sunday 30/03
£6
Monday 31/03
£6
Tuesday 01/04
£6
Wednesday 02/04
£6
Thursday 03/04
£6
Friday 04/04
£6
Saturday 05/04
£6
Sunday 06/04
£6
Monday 07/04
£6
Tuesday 08/04
£6
Wednesday 09/04
£6
Thursday 10/04
£6
Friday 11/04
£6
Saturday 12/04
£6
Sunday 13/04
£8
Monday 14/04
£6
Tuesday 15/04
£6
Wednesday 16/04
£6
Thursday 17/04
£11
Friday 18/04
£6
Saturday 19/04
£6
Sunday 20/04

The cheapest time to travel from Santiago, RM to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to La Serena, for the next 30 days.
With a price starting from £6, Tuesday is the cheapest day for a coach from Santiago, RM to La Serena. Monday instead is the most expensive day with prices starting from £6.
Morning is the cheapest day time for bus tickets from Santiago, RM to La Serena, with £6. Night is the most expensive time of the day with prices starting from £14.

How to save money travelling from Santiago, RM to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago, RM to La Serena are also emptier.

Latest reviews for coach companies on the route Santiago, RM - La Serena

FlixBus
Rocío Santana , 22/11/2024
Malísima experiencia con un hombre del personal, a media hora de haber salido del terminal San Borja mi hija necesito usar el baño a lo que respondió que el baño era solo para ruta y que estaban aburr ... Malísima experiencia con un hombre del personal, a media hora de haber salido del terminal San Borja mi hija necesito usar el baño a lo que respondió que el baño era solo para ruta y que estaban aburridos que las personas le hicieran ( del 2) , cosa que entiendo perfectamente, pero fue bastante grosero y retador y con la voz alzada, pésima experiencia no respondí porque estaba con mi hija pero nunca más usaré este servicio.
Condor Bus
Camila , 07/11/2024
Pésima experiencia, en bus de verdad tienen un olor demasiado hediondo es insoportable, además no tienen aire acondicionado y hizo mucho frío yo viaje de noche y pase demasiado frío, gente del bus le ... Pésima experiencia, en bus de verdad tienen un olor demasiado hediondo es insoportable, además no tienen aire acondicionado y hizo mucho frío yo viaje de noche y pase demasiado frío, gente del bus le pidió al chofer copiloto subir la temperatura y jamás lo hizo La verdad nunca mas viajo con ellos
Pullman San Andres
Ernesto, 12/09/2024
Viajo regularmente entre Santiago y La Serena y v/v, en Buses salón cama. es la primera vez que tomo esta empresa y en realidad no volvería a tomarla. Las razones: GPS DESCONECTADO por tanto se DESC ... Viajo regularmente entre Santiago y La Serena y v/v, en Buses salón cama. es la primera vez que tomo esta empresa y en realidad no volvería a tomarla. Las razones: GPS DESCONECTADO por tanto se DESCONOCE el nombre del conductor, cuanto tiempo lleva conduciendo y a qué velocidad estamos transitando. Maquina NO SANITIZADA da desconfianza sentarse en los asientos con los apoyacabezas negros de suciedad y sin funda de protección lo mismo pasa con los cinturones de seguridad también muy sucios. Esta máquina salió a las 12:30 PM desde terminal San Borja con destino a Arica, (yo bajo el La Serena)
Pluss Chile
Sramirez , 12/09/2024
Voy viajando en Salón cama y literal que voy atrapada entre mi asiento y el respaldo del asiento en frente de mi. El nivel de inclinación de los asientos supera lo permitido quedando prácticamente atr ... Voy viajando en Salón cama y literal que voy atrapada entre mi asiento y el respaldo del asiento en frente de mi. El nivel de inclinación de los asientos supera lo permitido quedando prácticamente atrapada, tienes el respaldo de la persona que va delante sobre tus piernas sin poder moverte y eso que soy delgada, imagino a alguien de mayor dimensión o un adulto mayor, además del mal olor en el bus es horrible. No viajo más en esta línea.

All bus stations and stops in Santiago, RM and La Serena

The map below shows you where to find all the bus stations in Santiago, RM and La Serena.

Service and Comfort on the bus from Santiago, RM to La Serena

Want to know which seat classes are available on the coaches from Santiago, RM to La Serena? Or which bus companies serve the route Santiago, RM to La Serena? Below you will find answers to your questions.

FAQs about the Santiago, RM to La Serena bus

How much does a Santiago, RM - La Serena coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santiago, RM - La Serena bus trip is available from £6 and takes 7h 10m. Compare offers and save money!

How much could I save by comparing buses from Santiago, RM to La Serena?

The connection Santiago, RM to La Serena is offered by 14 companies with ticket prices ranging from £6 to £26. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Santiago, RM - La Serena route on average every day?

Each day, the bus route from Santiago, RM to La Serena is offered by roughly 236 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to La Serena from Santiago, RM take?

The quickest coach from Santiago, RM to La Serena is provided by Pullman Bus and takes 5h 20m. Coach tickets for this connection cost £13. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santiago, RM to La Serena?

The earliest bus to La Serena departs from Santiago, RM at 00:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santiago, RM to La Serena?

The latest bus to La Serena departs from Santiago, RM at 23:59. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santiago, RM - La Serena route?

Passengers looking to travel from Santiago, RM to La Serena can travel with Turbus, Cikbus Elité and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santiago, RM and La Serena?

You can check all the direct connections between Santiago, RM and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Turbus, Cikbus Elité and FlixBus.

What can I take with me on the bus to La Serena from Santiago, RM?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santiago, RM La Serena bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to La Serena on your planned travel date.

Available seat classes which are offered on the bus route Santiago, RM to La Serena

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to La Serena

Here’s an overview of the most popular bus routes to Santiago, RM and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!
Coach to Santiago, RM from Iquique Coach to Santiago, RM from Iquique
Bus from Coquimbo to Santiago, RM Bus from Coquimbo to Santiago, RM
Coach Concepción to Santiago, RM Coach Concepción to Santiago, RM
Buses Copiapó to Santiago, RM Buses Copiapó to Santiago, RM
Bus from Valparaíso (CL) to La Serena Bus from Valparaíso (CL) to La Serena
Bus Antofagasta to La Serena Bus Antofagasta to La Serena
Iquique to La Serena coach Iquique to La Serena coach
Coach Arica, AP to La Serena Coach Arica, AP to La Serena
Popular Airport Transfers to Santiago, RM and to La Serena
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