Bus tickets São Paulo to Santa Cruz de la Sierra from £186

Compare all the coach companies and find the best price with CheckMyBus
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from São Paulo to Santa Cruz de la Sierra

Here is a selection of the cheapest bus trips from the schedule from São Paulo to Santa Cruz de la Sierra from various bus operators like La Preferida Bus for the next days.

today
£208
tomorrow
£208
Wednesday
Thursday
£208
Friday
Saturday
£208
Sunday
£208

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
La Preferida Bus 38h 30m 13:00 São Paulo Barra Funda Bus Station 03:30 Santa Cruz de la Sierra Terminal Bimodal  First Class £208
  • Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £71? You can find the corresponding connections below.
    • DeÔnibus
      50h 0m
      0
      15:00
      São Paulo
      Tietê Bus Station
      12:26
      Asunción, PY
      Coach Station
      0
      DeÔnibus
      First Class
      £81
      • Waiting Time 7h 34m
    • Plataforma 10
      21h 0m
      0
      20:00
      Asunción, PY
      Coach Station
      16:00
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Premium Economy
      £56
    Travel time is 11h 30m longer, but you will save £71

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
La Preferida Bus 38h 30m 13:00 São Paulo Barra Funda Bus Station 03:30 Santa Cruz de la Sierra Terminal Bimodal  First Class £208
  • Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £71? You can find the corresponding connections below.
    • DeÔnibus
      50h 0m
      0
      15:00
      São Paulo
      Tietê Bus Station
      12:26
      Asunción, PY
      Coach Station
      0
      DeÔnibus
      First Class
      £81
      • Waiting Time 7h 34m
    • Plataforma 10
      21h 0m
      0
      20:00
      Asunción, PY
      Coach Station
      16:00
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Premium Economy
      £56
    Travel time is 11h 30m longer, but you will save £71

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
La Preferida Bus 38h 30m 13:00 São Paulo Barra Funda Bus Station 03:30 Santa Cruz de la Sierra Terminal Bimodal  First Class £208
  • Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £71? You can find the corresponding connections below.
    • DeÔnibus
      50h 0m
      0
      15:00
      São Paulo
      Tietê Bus Station
      12:26
      Asunción, PY
      Coach Station
      0
      DeÔnibus
      First Class
      £81
      • Waiting Time 7h 34m
    • Plataforma 10
      21h 0m
      0
      20:00
      Asunción, PY
      Coach Station
      16:00
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Premium Economy
      £56
    Travel time is 11h 30m longer, but you will save £71

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
La Preferida Bus 38h 30m 13:00 São Paulo Barra Funda Bus Station 03:30 Santa Cruz de la Sierra Terminal Bimodal  First Class £208
  • Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £71? You can find the corresponding connections below.
    • DeÔnibus
      50h 0m
      0
      15:00
      São Paulo
      Tietê Bus Station
      12:26
      Asunción, PY
      Coach Station
      0
      DeÔnibus
      First Class
      £81
      • Waiting Time 7h 34m
    • Plataforma 10
      21h 0m
      0
      20:00
      Asunción, PY
      Coach Station
      16:00
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Premium Economy
      £56
    Travel time is 11h 30m longer, but you will save £71

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
La Preferida Bus 38h 30m 13:00 São Paulo Barra Funda Bus Station 03:30 Santa Cruz de la Sierra Terminal Bimodal  First Class £208
  • Did you know that if you travel from São Paulo to Santa Cruz de la Sierra via Asunción, PY, you can save more than £71? You can find the corresponding connections below.
    • DeÔnibus
      50h 0m
      0
      15:00
      São Paulo
      Tietê Bus Station
      12:26
      Asunción, PY
      Coach Station
      0
      DeÔnibus
      First Class
      £81
      • Waiting Time 7h 34m
    • Plataforma 10
      21h 0m
      0
      20:00
      Asunción, PY
      Coach Station
      16:00
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Premium Economy
      £56
    Travel time is 11h 30m longer, but you will save £71

Best Price Offer: The price for the cheapest coach from São Paulo to Santa Cruz de la Sierra is £186 on 01/01/2026. Flexible travellers save on ticket prices.


Facts about coaches from São Paulo to Santa Cruz de la Sierra

Compare all providers like La Preferida Bus that travel 1 times every day by bus from São Paulo to Santa Cruz de la Sierra in one click! Book your bus ticket from São Paulo to Santa Cruz de la Sierra starting from £186!

Cheapest Bus £186
Fastest Bus 38h 30m
Earliest Coach 13:00
Latest Coach 13:00
Daily Bus Connections 1 Ø
Distance 1,835.4 km
Coach Companies La Preferida Bus

Cheapest coach connections from São Paulo to Santa Cruz de la Sierra

Every day, 1 buses from 1 coach companies leave São Paulo for Santa Cruz de la Sierra: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 15/12/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 15/12
£208
Tuesday 16/12
£208
Wednesday 17/12
Thursday 18/12
£208
Friday 19/12
Saturday 20/12
£208
Sunday 21/12
£208
Monday 22/12
£208
Tuesday 23/12
£208
Wednesday 24/12
£208
Thursday 25/12
Friday 26/12
Saturday 27/12
Sunday 28/12
Monday 29/12
£208
Tuesday 30/12
£208
Wednesday 31/12
Thursday 01/01
£186
Friday 02/01
Saturday 03/01
£186
Sunday 04/01
Monday 05/01
£186
Tuesday 06/01
£186
Wednesday 07/01
Thursday 08/01
Friday 09/01
£186
Saturday 10/01
Sunday 11/01

How to save money travelling from São Paulo to Santa Cruz de la Sierra

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from São Paulo to Santa Cruz de la Sierra in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from São Paulo to Santa Cruz de la Sierra, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from São Paulo to Santa Cruz de la Sierra are also emptier.

All bus stations and stops in São Paulo and Santa Cruz de la Sierra

The map below shows you where to find all the bus stations in São Paulo and Santa Cruz de la Sierra.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from São Paulo to Santa Cruz de la Sierra? Compare all modes of transports from São Paulo to Santa Cruz de la Sierra.

Service and Comfort on the bus from São Paulo to Santa Cruz de la Sierra

Want to know which seat classes are available on the coaches from São Paulo to Santa Cruz de la Sierra? Or which bus companies serve the route São Paulo to Santa Cruz de la Sierra? Below you will find answers to your questions.

FAQs about the São Paulo to Santa Cruz de la Sierra bus

How much does a São Paulo - Santa Cruz de la Sierra coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the São Paulo - Santa Cruz de la Sierra bus trip is available from £186 and takes 38h 30m. Compare offers and save money!

How much could I save by comparing buses from São Paulo to Santa Cruz de la Sierra?

The connection São Paulo to Santa Cruz de la Sierra is offered by 1 companies with ticket prices ranging from £186 to £208. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the São Paulo - Santa Cruz de la Sierra route on average every day?

Each day, the bus route from São Paulo to Santa Cruz de la Sierra is offered by roughly 1 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santa Cruz de la Sierra from São Paulo take?

The quickest coach from São Paulo to Santa Cruz de la Sierra is provided by La Preferida Bus and takes 38h 30m. Coach tickets for this connection cost £208. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from São Paulo to Santa Cruz de la Sierra?

The earliest bus to Santa Cruz de la Sierra departs from São Paulo at 13:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from São Paulo to Santa Cruz de la Sierra?

The latest bus to Santa Cruz de la Sierra departs from São Paulo at 13:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the São Paulo - Santa Cruz de la Sierra route?

Passengers looking to travel from São Paulo to Santa Cruz de la Sierra can travel with La Preferida Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between São Paulo and Santa Cruz de la Sierra?

You can check all the direct connections between São Paulo and Santa Cruz de la Sierra by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: La Preferida Bus.

What can I take with me on the bus to Santa Cruz de la Sierra from São Paulo?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the São Paulo Santa Cruz de la Sierra bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the São Paulo Santa Cruz de la Sierra bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from São Paulo to Santa Cruz de la Sierra on your planned travel date.

How does CheckMyBus find the best bus deals from São Paulo to Santa Cruz de la Sierra?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between São Paulo and Santa Cruz de la Sierra. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from São Paulo to Santa Cruz de la Sierra?

Prices and availability for 1 trips between São Paulo and Santa Cruz de la Sierra change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route São Paulo to Santa Cruz de la Sierra

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to São Paulo and to Santa Cruz de la Sierra

Here’s an overview of the most popular bus routes to São Paulo and to Santa Cruz de la Sierra. Simply click on the connection of your choice, and you will find all the details about your bus route!
Coach Recife, PE to São Paulo Coach Recife, PE to São Paulo
Coach to São Paulo from Fortaleza, CE Coach to São Paulo from Fortaleza, CE
Coaches Feira de Santana, BA to São Paulo Coaches Feira de Santana, BA to São Paulo
Bus from Arapiraca, AL to São Paulo Bus from Arapiraca, AL to São Paulo
Bus Sucre to Santa Cruz de la Sierra Bus Sucre to Santa Cruz de la Sierra
Bus to Santa Cruz de la Sierra from Oruro Bus to Santa Cruz de la Sierra from Oruro
Coaches Buenos Aires to Santa Cruz de la Sierra Coaches Buenos Aires to Santa Cruz de la Sierra
Corumbá to Santa Cruz de la Sierra coach Corumbá to Santa Cruz de la Sierra coach
Popular Airport Transfers to São Paulo and to Santa Cruz de la Sierra
CheckMyBus › Coaches in Brazil › Coach to São Paulo › Coach to Santa Cruz de la Sierra

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

deals,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

for

ads

personalisation.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.