What is the best way to travel from Florence to Lyon?
Looking for a trip? Check and compare all the available Buses and Flights to Lyon from Florence. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Florence?
You can reach Lyon with just £21 by taking a Bus from Itabus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus10h 40m012:00FlorenceVilla Costanza Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 22:40:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 40m
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FlixBus11h 40m021:05FlorenceVilla Costanza Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 21:05:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 08:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 40m
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FlixBus11h 50m018:45FlorenceVilla Costanza Bus Station06:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 18:45:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 06:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 50m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 21:30:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 10m
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Itabus15h 35m013:20FlorenceVilla Costanza Bus Station04:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 13:20:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 04:55:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 15h 35m
Cheapest Buses Sunday
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FlixBus10h 40m012:00FlorenceVilla Costanza Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 22:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 40m
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 18:10:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 10m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 12:55:00. 50 Premium Economy ticket for £36 per person are available. Travel duration is 11h 50m
Cheapest Buses Monday
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 21:30:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 10m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 12:55:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 50m
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 18:10:00. 50 Economy ticket for £38 per person are available. Travel duration is 10h 40m
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FlixBus11h 15m012:30FlorenceVilla Costanza Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 12:30:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 23:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 15m
Cheapest Buses Tuesday
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FlixBus11h 40m021:05FlorenceVilla Costanza Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 21:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 08:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 40m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 12:55:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 50m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 10m
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FlixBus11h 50m018:45FlorenceVilla Costanza Bus Station06:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 18:45:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 06:35:00. 50 Economy ticket for £39 per person are available. Travel duration is 11h 50m
Cheapest Buses Wednesday
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 12:55:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 50m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 10m
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 18:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 10h 40m
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FlixBus10h 40m012:00FlorenceVilla Costanza Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 22:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 10h 40m
Cheapest Buses Thursday
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 12:55:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 50m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 21:30:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 10m
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FlixBus11h 15m012:30FlorenceVilla Costanza Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 12:30:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 23:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 11h 15m
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 18:10:00. 50 Economy ticket for £48 per person are available. Travel duration is 10h 40m
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Volotea1h 20m010:25Florence AirportFlorence Airport11:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 10:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 11:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 1h 20m
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Vueling Airlines7h 25m009:50Florence AirportFlorence Airport17:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 09:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 17:15:00. 50 Economy ticket for £83 per person are available. Travel duration is 7h 25m
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Air Dolomiti4h 25m008:00Florence AirportFlorence Airport12:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 08:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 12:25:00. 50 Economy ticket for £112 per person are available. Travel duration is 4h 25m
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KLM Cityhopper6h 45m006:40Florence AirportFlorence Airport13:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from KLM Cityhopper goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 06:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 13:25:00. 50 Economy ticket for £139 per person are available. Travel duration is 6h 45m
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Air France14h 20m020:45Florence AirportFlorence Airport11:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 20:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 20/12/2025 11:05:00. 50 Economy ticket for £140 per person are available. Travel duration is 14h 20m
Cheapest Buses Friday
Cheapest Flights Friday
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 12:55:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 50m
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BlaBlaCar Bus11h 10m014:15FlorencePiazza della Stazione Bus Station01:25LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 20/12/2025 14:15:00 to Perrache Train Station, Lyon (France) arriving at 21/12/2025 01:25:00. 50 Economy ticket for £31 per person are available. Travel duration is 11h 10m
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BlaBlaCar Bus11h 0m019:10FlorencePiazza della Stazione Bus Station06:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 20/12/2025 19:10:00 to Perrache Train Station, Lyon (France) arriving at 21/12/2025 06:10:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 0m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 21:30:00. 50 Premium Economy ticket for £38 per person are available. Travel duration is 11h 10m
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FlixBus11h 15m012:30FlorenceVilla Costanza Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 12:30:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 23:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 11h 15m
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Vueling Airlines35h 10m006:45Florence AirportFlorence Airport17:55Saint Étienne–Bouthéon AirportSaint Étienne–Bouthéon Airport0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 20/12/2025 06:45:00 to Saint Étienne–Bouthéon Airport, Saint Étienne–Bouthéon Airport (France) arriving at 21/12/2025 17:55:00. 50 Economy ticket for £343 per person are available. Travel duration is 35h 10m
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Vueling Airlines22h 45m019:10Florence AirportFlorence Airport17:55Saint Étienne–Bouthéon AirportSaint Étienne–Bouthéon Airport0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 20/12/2025 19:10:00 to Saint Étienne–Bouthéon Airport, Saint Étienne–Bouthéon Airport (France) arriving at 21/12/2025 17:55:00. 50 Economy ticket for £370 per person are available. Travel duration is 22h 45m
Cheapest Buses Saturday
Cheapest Flights Saturday
What are the fastest trips from Florence to Lyon?
You can get to Lyon from Florence in just 1h 20m with a Flight from Volotea. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus10h 40m012:00FlorenceVilla Costanza Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 22:40:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 21:30:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 10m
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FlixBus11h 40m021:05FlorenceVilla Costanza Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 21:05:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 08:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 40m
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FlixBus11h 50m018:45FlorenceVilla Costanza Bus Station06:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 18:45:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 06:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 50m
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Itabus15h 35m013:20FlorenceVilla Costanza Bus Station04:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 14/12/2025 13:20:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 04:55:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 15h 35m
Fastest Buses Sunday
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FlixBus10h 40m012:00FlorenceVilla Costanza Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 22:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 40m
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 18:10:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 10m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 15/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 12:55:00. 50 Premium Economy ticket for £36 per person are available. Travel duration is 11h 50m
Fastest Buses Monday
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 18:10:00. 50 Economy ticket for £38 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 21:30:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 10m
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FlixBus11h 15m012:30FlorenceVilla Costanza Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 12:30:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 23:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 15m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 16/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 12:55:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 50m
Fastest Buses Tuesday
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 10m
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FlixBus11h 40m021:05FlorenceVilla Costanza Bus Station08:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 21:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 08:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 40m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 12:55:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 50m
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FlixBus11h 50m018:45FlorenceVilla Costanza Bus Station06:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 17/12/2025 18:45:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 06:35:00. 50 Economy ticket for £39 per person are available. Travel duration is 11h 50m
Fastest Buses Wednesday
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 18:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 10h 40m
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FlixBus10h 40m012:00FlorenceVilla Costanza Bus Station22:40LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 22:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 10m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 18/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 12:55:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 50m
Fastest Buses Thursday
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Volotea1h 20m010:25Florence AirportFlorence Airport11:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 10:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 11:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 1h 20m
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Air Dolomiti4h 25m008:00Florence AirportFlorence Airport12:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 08:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 12:25:00. 50 Economy ticket for £112 per person are available. Travel duration is 4h 25m
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KLM Cityhopper6h 45m006:40Florence AirportFlorence Airport13:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from KLM Cityhopper goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 06:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 13:25:00. 50 Economy ticket for £139 per person are available. Travel duration is 6h 45m
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Vueling Airlines7h 25m009:50Florence AirportFlorence Airport17:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 09:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 19/12/2025 17:15:00. 50 Economy ticket for £83 per person are available. Travel duration is 7h 25m
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Air France14h 20m020:45Florence AirportFlorence Airport11:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 19/12/2025 20:45:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 20/12/2025 11:05:00. 50 Economy ticket for £140 per person are available. Travel duration is 14h 20m
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FlixBus10h 40m007:30FlorenceVilla Costanza Bus Station18:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 18:10:00. 50 Economy ticket for £48 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 21:30:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 10m
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FlixBus11h 15m012:30FlorenceVilla Costanza Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 12:30:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 23:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 11h 15m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 19/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 12:55:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 50m
Fastest Flights Friday
Fastest Buses Friday
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BlaBlaCar Bus11h 0m019:10FlorencePiazza della Stazione Bus Station06:10LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 20/12/2025 19:10:00 to Perrache Train Station, Lyon (France) arriving at 21/12/2025 06:10:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 0m
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BlaBlaCar Bus11h 10m014:15FlorencePiazza della Stazione Bus Station01:25LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 20/12/2025 14:15:00 to Perrache Train Station, Lyon (France) arriving at 21/12/2025 01:25:00. 50 Economy ticket for £31 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20FlorenceVilla Costanza Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 21:30:00. 50 Premium Economy ticket for £38 per person are available. Travel duration is 11h 10m
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FlixBus11h 15m012:30FlorenceVilla Costanza Bus Station23:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 12:30:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 23:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 11h 15m
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Itabus11h 50m001:05FlorenceVilla Costanza Bus Station12:55LyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 20/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 12:55:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 50m
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Vueling Airlines22h 45m019:10Florence AirportFlorence Airport17:55Saint Étienne–Bouthéon AirportSaint Étienne–Bouthéon Airport0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 20/12/2025 19:10:00 to Saint Étienne–Bouthéon Airport, Saint Étienne–Bouthéon Airport (France) arriving at 21/12/2025 17:55:00. 50 Economy ticket for £370 per person are available. Travel duration is 22h 45m
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Vueling Airlines35h 10m006:45Florence AirportFlorence Airport17:55Saint Étienne–Bouthéon AirportSaint Étienne–Bouthéon Airport0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 20/12/2025 06:45:00 to Saint Étienne–Bouthéon Airport, Saint Étienne–Bouthéon Airport (France) arriving at 21/12/2025 17:55:00. 50 Economy ticket for £343 per person are available. Travel duration is 35h 10m
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Here you will find all operators and timetables for a
Bus from Florence to Lyon
What are the most popular stations in Florence and Lyon?
In Florence, you will usually depart from Santa Maria Novella Central Station, Villa Costanza Bus Station or Piazzale Montelungo Coach Stop, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Florence? With 6 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Florence and Lyon, you can pay as low as £21 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Volotea: you will get to Lyon in just 1h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Florence and Lyon are Itabus, FlixBus and Vueling Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Florence and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Scandicci or to Caluire-et-Cuire, and look at flights from Florence Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Florence to Lyon?
The most popular companies between Florence and Lyon, are Itabus, FlixBus and Vueling Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, FlixBus and BlaBlaCar Bus
Airlines: Vueling Airlines, Volotea, Air Dolomiti and 2 more.
All you need to know when you travel from Florence to Lyon
Check all information on comfort and services on all modes of transports from Florence to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Florence to Lyon
How can I reach Lyon from Florence?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to Lyon from Florence.
How far is Lyon from Florence?
The distance between Florence and Lyon is 552.2 km.
What is the most ecofriendly mode of transport between Florence and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 19 kgs, a car 94 kgs, and a flight 136 kgs.
What is the cheapest mode of transport from Florence to Lyon?
You can get to Lyon with just £21 by taking a Bus from Itabus.
What is the fastest way to get from Florence to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 20m with a Flight from Volotea.
More routes to Florence and to Lyon
Looking for more options? Here you can see the most popular routes to Florence and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Florence
- Berlin to Florence
- Bologna Airport to Florence
- Bologna to Florence
- Castrovillari to Florence
- Cosenza to Florence
- Frascineto to Florence
- Genoa to Florence
- Lagonegro to Florence
- Marseille to Florence
- Milan Malpensa Airport to Florence
- Milan to Florence
- Modena to Florence
- Naples to Florence
- Perugia to Florence
- Pescara to Florence
- Pisa Airport to Florence
- Pisa to Florence
- Rome Fiumicino Airport to Florence
- Rome to Florence
- San Benedetto del Tronto to Florence
- Siena to Florence
- Venice to Florence
- Vibo Valentia to Florence
- Zurich to Florence
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Bern to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Braga to Lyon
- Caen to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- Lisbon to Lyon
- Lloret de Mar to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Paris to Lyon
- Rome to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon

