How to get from Lyon to Brussels

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What is the best way to travel from Lyon to Brussels?

Looking for a trip? Check and compare all the available Buses, Carpool and Flights to Brussels from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
10h 5m
£17
£26
25
Car
7h 10m
£31
£33
2
Flight
1h 25m
£46
£150
31

What is the cheapest way to reach Brussels from Lyon?

You can reach Brussels with just £17 by taking a Bus from BlaBlaCar Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Friday
from £30
Saturday
from £25
Sunday
from £24
Monday
from £17
Tuesday
from £22
Wednesday
from £20
Thursday
from £20

    Cheapest Buses Friday

  • FlixBus
    11h 30m
    0
    04:05
    Lyon
    Perrache Bus Stop
    15:35
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £30
  • FlixBus
    14h 15m
    0
    05:20
    Lyon
    Perrache Bus Stop
    19:35
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £30
  • FlixBus
    11h 30m
    0
    00:50
    Lyon
    Perrache Bus Stop
    12:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £31
  • BlaBlaCar Bus
    12h 0m
    0
    02:45
    Lyon
    Perrache Train Station
    14:45
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £31

    Cheapest Buses Saturday

  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £25
  • BlaBlaCar Bus
    11h 40m
    0
    10:50
    Lyon
    Perrache Train Station
    22:30
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £27
  • BlaBlaCar Bus
    11h 35m
    0
    12:00
    Lyon
    Perrache Train Station
    23:35
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £27
  • FlixBus
    14h 15m
    0
    05:20
    Lyon
    Perrache Bus Stop
    19:35
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £28

    Cheapest Buses Sunday

  • BlaBlaCar Bus
    11h 0m
    0
    01:00
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £24
  • BlaBlaCar Bus
    10h 5m
    0
    03:25
    Lyon
    Perrache Train Station
    13:30
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £26
  • FlixBus
    12h 5m
    0
    00:15
    Lyon
    Perrache Bus Stop
    12:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £31
  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £31
  • Cheapest Flights Sunday

  • Volotea
    41h 35m
    0
    20:35
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    14:10
    Antwerp Airport
    Antwerp Airport
    0
    Volotea
    Economy
    from £164
  • Transavia France
    18h 35m
    0
    18:45
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    13:20
    Antwerp Airport
    Antwerp Airport
    0
    Transavia France
    Economy
    from £238
  • EasyJet Airline
    30h 20m
    0
    07:00
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    13:20
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £265
  • Vueling Airlines
    28h 0m
    0
    09:20
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    13:20
    Antwerp Airport
    Antwerp Airport
    0
    Vueling Airlines
    Economy
    from £292

    Cheapest Buses Monday

  • BlaBlaCar Bus
    12h 0m
    0
    02:45
    Lyon
    Perrache Train Station
    14:45
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £17
  • BlaBlaCar Bus
    10h 30m
    0
    01:30
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £20
  • BlaBlaCar Bus
    10h 25m
    0
    01:35
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £20
  • FlixBus
    11h 30m
    0
    02:30
    Lyon
    Perrache Bus Stop
    14:00
    Brussels
    North Station
    0
    FlixBus
    Economy
    £23
  • Cheapest Flights Monday

  • LC Perú
    23h 50m
    0
    08:00
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    07:50
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    LC Perú
    Economy
    from £65
  • EasyJet Airline
    9h 55m
    0
    07:35
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    17:30
    Brussels Airport
    Brussels Airport
    0
    EasyJet Airline
    Economy
    from £68
  • Vueling Airlines
    9h 50m
    0
    23:25
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    09:15
    Brussels Airport
    Brussels Airport
    0
    Vueling Airlines
    Economy
    from £69
  • EasyJet Airline
    6h 30m
    0
    10:40
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    17:10
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £91

    Cheapest Buses Tuesday

  • BlaBlaCar Bus
    10h 40m
    0
    01:20
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £22
  • BlaBlaCar Bus
    10h 35m
    0
    02:55
    Lyon
    Perrache Train Station
    13:30
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £22
  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £23
  • FlixBus
    11h 30m
    0
    02:30
    Lyon
    Perrache Bus Stop
    14:00
    Brussels
    North Station
    0
    FlixBus
    Economy
    £26

    Cheapest Buses Wednesday

  • FlixBus
    11h 50m
    0
    08:40
    Lyon
    Perrache Bus Stop
    20:30
    Brussels
    North Station
    0
    FlixBus
    Economy
    £20
  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £20
  • BlaBlaCar Bus
    11h 50m
    0
    00:10
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £25
  • FlixBus
    10h 45m
    0
    21:30
    Lyon
    Perrache Bus Stop
    08:15
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £29
  • Cheapest Flights Wednesday

  • EasyJet Airline
    8h 20m
    0
    10:15
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    18:35
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £46
  • EasyJet Airline
    8h 25m
    0
    07:15
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    15:40
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £47
  • EasyJet Airline
    7h 25m
    0
    14:40
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    22:05
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £55
  • Vueling Airlines
    6h 35m
    0
    09:20
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    15:55
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Vueling Airlines
    Economy
    from £58

    Cheapest Buses Thursday

  • BlaBlaCar Bus
    10h 25m
    0
    01:35
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £20
  • BlaBlaCar Bus
    12h 10m
    0
    02:45
    Lyon
    Perrache Train Station
    14:55
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £24
  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £25
  • FlixBus
    11h 0m
    0
    00:15
    Lyon
    Perrache Bus Stop
    11:15
    Brussels
    North Station
    0
    FlixBus
    Economy
    £27
  • Cheapest Carpool Thursday

  • BlaBlaCar
    7h 40m
    0
    12:00
    Lyon
    19:40
    Brussels
    0
    BlaBlaCar
    Economy
    from £31
  • BlaBlaCar
    7h 10m
    0
    12:00
    Lyon
    19:10
    Brussels
    0
    BlaBlaCar
    Economy
    from £35

What are the fastest trips from Lyon to Brussels?

You can get to Brussels from Lyon in just 1h 25m with a Flight from Brussels Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Friday
from 10h 25m
Saturday
from 10h 35m
Sunday
from 10h 5m
Monday
from 4h 5m
Tuesday
from 10h 35m
Wednesday
from 1h 25m
Thursday
from 7h 10m

    Fastest Buses Friday

  • BlaBlaCar Bus
    10h 25m
    0
    01:35
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £38
  • FlixBus
    11h 30m
    0
    04:05
    Lyon
    Perrache Bus Stop
    15:35
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £30
  • FlixBus
    11h 30m
    0
    00:50
    Lyon
    Perrache Bus Stop
    12:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £31
  • BlaBlaCar Bus
    12h 0m
    0
    02:45
    Lyon
    Perrache Train Station
    14:45
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £31

    Fastest Buses Saturday

  • BlaBlaCar Bus
    10h 35m
    0
    02:55
    Lyon
    Perrache Train Station
    13:30
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £28
  • BlaBlaCar Bus
    11h 35m
    0
    12:00
    Lyon
    Perrache Train Station
    23:35
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £27
  • BlaBlaCar Bus
    11h 40m
    0
    10:50
    Lyon
    Perrache Train Station
    22:30
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £27
  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £25

    Fastest Buses Sunday

  • BlaBlaCar Bus
    10h 5m
    0
    03:25
    Lyon
    Perrache Train Station
    13:30
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £26
  • BlaBlaCar Bus
    11h 0m
    0
    01:00
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £24
  • BlaBlaCar Bus
    11h 30m
    0
    03:45
    Lyon
    Perrache Train Station
    15:15
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £31
  • FlixBus
    12h 5m
    0
    00:15
    Lyon
    Perrache Bus Stop
    12:20
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £31
  • Fastest Flights Sunday

  • Transavia France
    18h 35m
    0
    18:45
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    13:20
    Antwerp Airport
    Antwerp Airport
    0
    Transavia France
    Economy
    from £238
  • Portugália Airlines
    24h 40m
    0
    12:40
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    13:20
    Antwerp Airport
    Antwerp Airport
    0
    Portugália Airlines
    Economy
    from £306
  • Vueling Airlines
    28h 0m
    0
    09:20
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    13:20
    Antwerp Airport
    Antwerp Airport
    0
    Vueling Airlines
    Economy
    from £292
  • EasyJet Airline
    30h 20m
    0
    07:00
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    13:20
    Antwerp Airport
    Antwerp Airport
    0
    EasyJet Airline
    Economy
    from £265

    Fastest Flights Monday

  • EasyJet Airline
    4h 5m
    0
    16:50
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    20:55
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £109
  • EasyJet Airline
    5h 15m
    0
    07:20
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    12:35
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £106
  • EasyJet Airline
    6h 30m
    0
    10:40
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    17:10
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    EasyJet Airline
    Economy
    from £91
  • Vueling Airlines
    9h 50m
    0
    23:25
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    09:15
    Brussels Airport
    Brussels Airport
    0
    Vueling Airlines
    Economy
    from £69
  • Fastest Buses Monday

  • BlaBlaCar Bus
    10h 25m
    0
    01:35
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £20
  • BlaBlaCar Bus
    10h 30m
    0
    01:30
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £20
  • FlixBus
    11h 30m
    0
    02:30
    Lyon
    Perrache Bus Stop
    14:00
    Brussels
    North Station
    0
    FlixBus
    Economy
    £23
  • BlaBlaCar Bus
    12h 0m
    0
    02:45
    Lyon
    Perrache Train Station
    14:45
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £17

    Fastest Buses Tuesday

  • BlaBlaCar Bus
    10h 35m
    0
    02:55
    Lyon
    Perrache Train Station
    13:30
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £22
  • BlaBlaCar Bus
    10h 40m
    0
    01:20
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £22
  • FlixBus
    11h 30m
    0
    02:30
    Lyon
    Perrache Bus Stop
    14:00
    Brussels
    North Station
    0
    FlixBus
    Economy
    £26
  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £23

    Fastest Flights Wednesday

  • Brussels Airlines
    1h 25m
    0
    13:10
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    14:35
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from £179
  • British Airways
    4h 10m
    0
    13:35
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    17:45
    Brussels Airport
    Brussels Airport
    0
    British Airways
    Economy
    from £196
  • Vueling Airlines
    6h 20m
    0
    09:20
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    15:40
    Brussels Airport
    Brussels Airport
    0
    Vueling Airlines
    Economy
    from £80
  • Vueling Airlines
    6h 35m
    0
    09:20
    Lyons St. Exupery Airport
    Aéroport St Exupéry Coach Station
    15:55
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Vueling Airlines
    Economy
    from £58
  • Fastest Buses Wednesday

  • FlixBus
    10h 45m
    0
    21:30
    Lyon
    Perrache Bus Stop
    08:15
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    £29
  • FlixBus
    11h 50m
    0
    08:40
    Lyon
    Perrache Bus Stop
    20:30
    Brussels
    North Station
    0
    FlixBus
    Economy
    £20
  • BlaBlaCar Bus
    11h 50m
    0
    00:10
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £25
  • FlixBus
    13h 40m
    0
    21:30
    Lyon
    Perrache Bus Stop
    11:10
    Brussels
    North Station
    0
    FlixBus
    Economy
    £20

    Fastest Carpool Thursday

  • BlaBlaCar
    7h 10m
    0
    12:00
    Lyon
    19:10
    Brussels
    0
    BlaBlaCar
    Economy
    from £35
  • BlaBlaCar
    7h 40m
    0
    12:00
    Lyon
    19:40
    Brussels
    0
    BlaBlaCar
    Economy
    from £31
  • Fastest Buses Thursday

  • BlaBlaCar Bus
    10h 25m
    0
    01:35
    Lyon
    Perrache Train Station
    12:00
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £20
  • FlixBus
    11h 0m
    0
    00:15
    Lyon
    Perrache Bus Stop
    11:15
    Brussels
    North Station
    0
    FlixBus
    Economy
    £27
  • FlixBus
    11h 45m
    0
    19:00
    Lyon
    Perrache Bus Stop
    06:45
    Brussels
    North Station
    0
    FlixBus
    Economy
    £27
  • BlaBlaCar Bus
    12h 10m
    0
    02:45
    Lyon
    Perrache Train Station
    14:55
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    £24
Here you will find all operators and timetables for a Bus from Lyon to Brussels

What are the most popular stations in Lyon and Brussels?

In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Brussels from Lyon? With 8 connections between 3 Bus, Carpool and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Brussels, you can pay as low as £17 with a Bus from BlaBlaCar Bus.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Brussels Airlines: you will get to Brussels in just 1h 25m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Brussels are FlixBus, BlaBlaCar Bus and EasyJet Airline, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Lyon and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Saint-Gilles, and look at flights from Lyons St. Exupery Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Lyon to Brussels?

The most popular companies between Lyon and Brussels, are FlixBus, BlaBlaCar Bus and EasyJet Airline. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and BlaBlaCar Bus

Airlines: EasyJet Airline, Vueling Airlines, Volotea and 8 more.

All you need to know when you travel from Lyon to Brussels

Check all information on comfort and services on all modes of transports from Lyon to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Lyon to Brussels

How can I reach Brussels from Lyon?

Every day, there are on average 8 connections between Bus, Carpool and Flight, with which you can get to Brussels from Lyon.

How far is Brussels from Lyon?

The distance between Lyon and Brussels is 567.4 km.

What is the most ecofriendly mode of transport between Lyon and Brussels?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 20 kgs, a car 96 kgs, and a flight 140 kgs.

What is the cheapest mode of transport from Lyon to Brussels?

You can get to Brussels with just £17 by taking a Bus from BlaBlaCar Bus.

What is the fastest way to get from Lyon to Brussels?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 25m with a Flight from Brussels Airlines.

More routes to Lyon and to Brussels

Looking for more options? Here you can see the most popular routes to Lyon and to Brussels. Simply click on a connection, and you’ll find all the details about the route!

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