How to get from Mainz to Prague

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What is the best way to travel from Mainz to Prague?

Looking for a trip? Check and compare all the available Buses and Flights to Prague from Mainz. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
6h 45m
£22
£31
13
Flight
1h 0m
£126
£213
119

What is the cheapest way to reach Prague from Mainz?

You can reach Prague with just £22 by taking a Bus from RegioJet, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Monday
from £22
Tuesday
from £24
Wednesday
from £155
Thursday
from £157
Friday
from £26
Saturday
from £35
Sunday
from £34

    Cheapest Buses Monday

  • RegioJet
    6h 45m
    0
    22:00
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    04:45
    Prague
    Train station Wilsonova
    0
    RegioJet
    Economy
    £22
  • FlixBus
    8h 55m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:35
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £23
  • FlixBus
    8h 30m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £23
  • FlixBus
    11h 10m
    0
    23:30
    Mainz
    Central Station
    10:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £23
  • Cheapest Flights Monday

  • EasyJet Airline
    10h 50m
    0
    20:10
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    07:00
    Prague Airport
    Prague Airport - T1/2
    0
    EasyJet Airline
    Economy
    from £126
  • LOT Polish Airlines / Polskie Linie Lotnicze
    13h 25m
    0
    19:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:15
    Prague Airport
    Prague Airport - T1/2
    0
    LOT Polish Airlines / Polskie Linie Lotnicze
    Economy
    from £127
  • SAS Scandinavian Airlines
    4h 55m
    0
    15:20
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    20:15
    Prague Airport
    Prague Airport - T1/2
    0
    SAS Scandinavian Airlines
    Economy
    from £151
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £153
  • KLM Cityhopper
    6h 30m
    0
    14:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    20:45
    Prague Airport
    Prague Airport - T1/2
    0
    KLM Cityhopper
    Economy
    from £196

    Cheapest Buses Tuesday

  • FlixBus
    8h 30m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £24
  • FlixBus
    8h 55m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:35
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £24
  • FlixBus
    7h 25m
    0
    23:30
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £24
  • FlixBus
    9h 25m
    0
    23:30
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £26
  • FlixBus
    8h 55m
    0
    04:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:10
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £26
  • Cheapest Flights Tuesday

  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171

    Cheapest Flights Wednesday

  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £155
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £155
  • Lufthansa
    1h 0m
    0
    09:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £223
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £230
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £230

    Cheapest Flights Thursday

  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £157
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £157
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £275
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £275
  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £406

    Cheapest Buses Friday

  • FlixBus
    8h 30m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £26
  • FlixBus
    8h 55m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:35
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £26
  • FlixBus
    7h 25m
    0
    23:30
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £27
  • FlixBus
    10h 45m
    0
    00:45
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    11:30
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £32
  • FlixBus
    9h 0m
    0
    01:05
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £32
  • Cheapest Flights Friday

  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £135
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172
  • Lufthansa
    1h 0m
    0
    12:20
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:20
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172

    Cheapest Buses Saturday

  • FlixBus
    10h 45m
    0
    05:15
    Mainz
    Central Station
    16:00
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £35
  • FlixBus
    10h 25m
    0
    05:15
    Mainz
    Central Station
    15:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £35
  • FlixBus
    11h 10m
    0
    23:30
    Mainz
    Central Station
    10:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £37
  • FlixBus
    8h 25m
    0
    16:00
    Mainz
    Central Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £38
  • FlixBus
    8h 5m
    0
    16:00
    Mainz
    Central Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £38
  • Cheapest Flights Saturday

  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £156
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £352
  • Lufthansa
    1h 0m
    0
    12:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £473

    Cheapest Buses Sunday

  • FlixBus
    11h 10m
    0
    23:30
    Mainz
    Central Station
    10:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £34
  • FlixBus
    10h 45m
    0
    05:15
    Mainz
    Central Station
    16:00
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £35
  • FlixBus
    10h 25m
    0
    05:15
    Mainz
    Central Station
    15:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £35
  • FlixBus
    8h 25m
    0
    16:00
    Mainz
    Central Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £54
  • FlixBus
    8h 5m
    0
    16:00
    Mainz
    Central Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £54
  • Cheapest Flights Sunday

  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £153
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £153
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £278
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £278
  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £477

What are the fastest trips from Mainz to Prague?

You can get to Prague from Mainz in just 1h 0m with a Flight from Lufthansa. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Monday
from 1h 0m
Tuesday
from 1h 0m
Wednesday
from 1h 0m
Thursday
from 1h 0m
Friday
from 1h 0m
Saturday
from 1h 0m
Sunday
from 1h 0m

    Fastest Flights Monday

  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £153
  • SAS Scandinavian Airlines
    4h 55m
    0
    15:20
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    20:15
    Prague Airport
    Prague Airport - T1/2
    0
    SAS Scandinavian Airlines
    Economy
    from £151
  • KLM Cityhopper
    6h 30m
    0
    14:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    20:45
    Prague Airport
    Prague Airport - T1/2
    0
    KLM Cityhopper
    Economy
    from £196
  • EasyJet Airline
    10h 50m
    0
    20:10
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    07:00
    Prague Airport
    Prague Airport - T1/2
    0
    EasyJet Airline
    Economy
    from £126
  • LOT Polish Airlines / Polskie Linie Lotnicze
    13h 25m
    0
    19:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:15
    Prague Airport
    Prague Airport - T1/2
    0
    LOT Polish Airlines / Polskie Linie Lotnicze
    Economy
    from £127
  • Fastest Buses Monday

  • RegioJet
    6h 45m
    0
    22:00
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    04:45
    Prague
    Train station Wilsonova
    0
    RegioJet
    Economy
    £22
  • FlixBus
    8h 30m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £23
  • FlixBus
    8h 55m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:35
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £23
  • FlixBus
    11h 10m
    0
    23:30
    Mainz
    Central Station
    10:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £23

    Fastest Flights Tuesday

  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £171
  • Fastest Buses Tuesday

  • FlixBus
    7h 25m
    0
    23:30
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £24
  • FlixBus
    8h 30m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £24
  • FlixBus
    8h 55m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:35
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £24
  • FlixBus
    8h 55m
    0
    04:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:10
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £26
  • FlixBus
    9h 25m
    0
    23:30
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £26

    Fastest Flights Wednesday

  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £155
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £155
  • Lufthansa
    1h 0m
    0
    09:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £223
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £230
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £230

    Fastest Flights Thursday

  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £157
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £157
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £275
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £275
  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £406

    Fastest Flights Friday

  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £135
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172
  • Lufthansa
    1h 0m
    0
    12:20
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:20
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £172
  • Fastest Buses Friday

  • FlixBus
    7h 25m
    0
    23:30
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    06:55
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £27
  • FlixBus
    8h 30m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £26
  • FlixBus
    8h 55m
    0
    10:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    19:35
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £26
  • FlixBus
    9h 0m
    0
    01:05
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £32
  • FlixBus
    10h 45m
    0
    00:45
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    11:30
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £32

    Fastest Flights Saturday

  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £156
  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £352
  • Lufthansa
    1h 0m
    0
    12:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £473
  • Fastest Buses Saturday

  • FlixBus
    8h 5m
    0
    16:00
    Mainz
    Central Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £38
  • FlixBus
    8h 25m
    0
    16:00
    Mainz
    Central Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £38
  • FlixBus
    10h 25m
    0
    05:15
    Mainz
    Central Station
    15:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £35
  • FlixBus
    10h 45m
    0
    05:15
    Mainz
    Central Station
    16:00
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £35
  • FlixBus
    11h 10m
    0
    23:30
    Mainz
    Central Station
    10:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £37

    Fastest Flights Sunday

  • Lufthansa
    1h 0m
    0
    16:50
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    17:50
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £153
  • Lufthansa
    1h 0m
    0
    22:15
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    23:15
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £153
  • Lufthansa
    1h 0m
    0
    08:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    09:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £278
  • Lufthansa
    1h 0m
    0
    09:55
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    10:55
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £278
  • Lufthansa
    1h 0m
    0
    12:40
    Frankfurt am Main Airport
    Frankfurt am Main Airport
    13:40
    Prague Airport
    Prague Airport - T1/2
    0
    Lufthansa
    Economy
    from £477
  • Fastest Buses Sunday

  • FlixBus
    8h 5m
    0
    16:00
    Mainz
    Central Station
    00:05
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £54
  • FlixBus
    8h 25m
    0
    16:00
    Mainz
    Central Station
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £54
  • FlixBus
    10h 25m
    0
    05:15
    Mainz
    Central Station
    15:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £35
  • FlixBus
    10h 45m
    0
    05:15
    Mainz
    Central Station
    16:00
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £35
  • FlixBus
    11h 10m
    0
    23:30
    Mainz
    Central Station
    10:40
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £34
Here you will find all operators and timetables for a Bus from Mainz to Prague

What are the most popular stations in Mainz and Prague?

In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Prague you will be arriving at ÚAN Florenc, Train station Wilsonova or Wilsonova Coach Station, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Prague from Mainz? With 8 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Prague, you can pay as low as £22 with a Bus from RegioJet.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa: you will get to Prague in just 1h 0m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Prague are Lufthansa, FlixBus and RegioJet, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Mainz and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Horoměřice, and look at flights from Frankfurt am Main Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Mainz to Prague?

The most popular companies between Mainz and Prague, are Lufthansa, FlixBus and RegioJet. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and RegioJet

Airlines: Lufthansa, EasyJet Airline, LOT Polish Airlines / Polskie Linie Lotnicze and 2 more.

All you need to know when you travel from Mainz to Prague

Check all information on comfort and services on all modes of transports from Mainz to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Mainz to Prague

How can I reach Prague from Mainz?

Every day, there are on average 8 connections between Bus and Flight, with which you can get to Prague from Mainz.

How far is Prague from Mainz?

The distance between Mainz and Prague is 442.1 km.

What is the most ecofriendly mode of transport between Mainz and Prague?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 15 kgs, a car 75 kgs, and a flight 109 kgs.

What is the cheapest mode of transport from Mainz to Prague?

You can get to Prague with just £22 by taking a Bus from RegioJet.

What is the fastest way to get from Mainz to Prague?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 0m with a Flight from Lufthansa.

More routes to Mainz and to Prague

Looking for more options? Here you can see the most popular routes to Mainz and to Prague. Simply click on a connection, and you’ll find all the details about the route!

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