Which bus from Chicago to San Diego is the best?
Check the bus schedule for Chicago to San Diego. Here is a selection of the cheapest coach trips for the next days from bus operators like Greyhound US or FlixBus. To see the full timetable for all coaches just use or search and compare.
Cheapest bus trips today
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Greyhound US72h 40m010:00ChicagoUnion Station10:40San DiegoBalboa Park0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 28/03/2025 10:00:00 to Balboa Park, San Diego (USA) arriving at 31/03/2025 10:40:00. 50 Economy ticket for £125 per person are available. Travel duration is 72h 40m
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Greyhound US55h 45m010:00ChicagoUnion Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 28/03/2025 10:00:00 to Old Town Transit Center, San Diego (USA) arriving at 30/03/2025 17:45:00. 50 Economy ticket for £128 per person are available. Travel duration is 55h 45m
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Greyhound US60h 10m022:30ChicagoDowntown Coach Station10:40San DiegoBalboa Park0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 28/03/2025 22:30:00 to Balboa Park, San Diego (USA) arriving at 31/03/2025 10:40:00. 50 Economy ticket for £135 per person are available. Travel duration is 60h 10m
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Greyhound US55h 25m006:10ChicagoDowntown Coach Station13:35San DiegoSDSU Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 28/03/2025 06:10:00 to SDSU Transit Center, San Diego (USA) arriving at 30/03/2025 13:35:00. 50 Economy ticket for £136 per person are available. Travel duration is 55h 25m
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Greyhound US63h 5m022:30ChicagoDowntown Coach Station13:35San DiegoSDSU Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 28/03/2025 22:30:00 to SDSU Transit Center, San Diego (USA) arriving at 31/03/2025 13:35:00. 50 Economy ticket for £136 per person are available. Travel duration is 63h 5m
Cheapest bus trips tomorrow
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Greyhound US49h 35m016:45ChicagoDowntown Coach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 29/03/2025 16:45:00 to San Ysidro Transit Center, San Diego (USA) arriving at 31/03/2025 18:20:00. 50 Economy ticket for £182 per person are available. Travel duration is 49h 35m
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Greyhound US56h 20m010:00ChicagoUnion Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 29/03/2025 10:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 31/03/2025 18:20:00. 50 Economy ticket for £196 per person are available. Travel duration is 56h 20m
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FlixBus56h 5m006:10ChicagoDowntown Coach Station21:00Kansas CityGreyhound Bus Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 31/03/2025 06:10:00 to Greyhound Bus Station, Kansas City (USA) arriving at 31/03/2025 21:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 14h 50m
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FlixBus39h 55m022:20Kansas CityGreyhound Bus Station14:15San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Kansas City (USA) at 31/03/2025 22:20:00 to Old Town Transit Center, San Diego (USA) arriving at 02/04/2025 14:15:00. 50 Economy ticket for £97 per person are available. Travel duration is 39h 55m
Waiting Time 1h 20m -
Cheapest bus trips Sunday
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Greyhound US52h 45m016:45ChicagoDowntown Coach Station21:30San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 30/03/2025 16:45:00 to Seaport Village, San Diego (USA) arriving at 01/04/2025 21:30:00. 50 Economy ticket for £102 per person are available. Travel duration is 52h 45m
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Greyhound US49h 0m016:45ChicagoDowntown Coach Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 30/03/2025 16:45:00 to Old Town Transit Center, San Diego (USA) arriving at 01/04/2025 17:45:00. 50 Economy ticket for £103 per person are available. Travel duration is 49h 0m
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Greyhound US71h 0m022:30ChicagoDowntown Coach Station21:30San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 30/03/2025 22:30:00 to Seaport Village, San Diego (USA) arriving at 02/04/2025 21:30:00. 50 Economy ticket for £106 per person are available. Travel duration is 71h 0m
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Greyhound US55h 20m014:10Chicago95th Red Line Station21:30San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 30/03/2025 14:10:00 to Seaport Village, San Diego (USA) arriving at 01/04/2025 21:30:00. 50 Economy ticket for £114 per person are available. Travel duration is 55h 20m
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Greyhound US60h 40m020:35Chicago95th Red Line Station09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 30/03/2025 20:35:00 to Old Town Transit Center, San Diego (USA) arriving at 02/04/2025 09:15:00. 50 Economy ticket for £115 per person are available. Travel duration is 60h 40m
Cheapest bus trips Monday
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Greyhound US61h 50m010:00ChicagoUnion Station23:50San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 31/03/2025 10:00:00 to Old Town Transit Center, San Diego (USA) arriving at 02/04/2025 23:50:00. 50 Economy ticket for £110 per person are available. Travel duration is 61h 50m
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Greyhound US61h 50m010:00ChicagoCanal & Van Buren23:50San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 31/03/2025 10:00:00 to Old Town Transit Center, San Diego (USA) arriving at 02/04/2025 23:50:00. 50 Economy ticket for £112 per person are available. Travel duration is 61h 50m
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Greyhound US72h 40m010:00ChicagoCanal & Van Buren10:40San DiegoBalboa Park0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 31/03/2025 10:00:00 to Balboa Park, San Diego (USA) arriving at 03/04/2025 10:40:00. 50 Economy ticket for £113 per person are available. Travel duration is 72h 40m
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FlixBus63h 15m023:50Chicago95th Red Line Station15:05San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 31/03/2025 23:50:00 to Old Town Transit Center, San Diego (USA) arriving at 03/04/2025 15:05:00. 50 Economy ticket for £129 per person are available. Travel duration is 63h 15m
Cheapest bus trips Tuesday
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Greyhound US56h 55m006:10ChicagoDowntown Coach Station15:05San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 01/04/2025 06:10:00 to Old Town Transit Center, San Diego (USA) arriving at 03/04/2025 15:05:00. 50 Economy ticket for £155 per person are available. Travel duration is 56h 55m
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Greyhound US56h 25m006:10ChicagoDowntown Coach Station14:35San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 01/04/2025 06:10:00 to La Jolla Village, San Diego (USA) arriving at 03/04/2025 14:35:00. 50 Economy ticket for £155 per person are available. Travel duration is 56h 25m
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Greyhound US72h 40m010:00ChicagoUnion Station10:40San DiegoBalboa Park0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 01/04/2025 10:00:00 to Balboa Park, San Diego (USA) arriving at 04/04/2025 10:40:00. 50 Economy ticket for £160 per person are available. Travel duration is 72h 40m
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Greyhound US60h 10m022:30ChicagoDowntown Coach Station10:40San DiegoBalboa Park0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 01/04/2025 22:30:00 to Balboa Park, San Diego (USA) arriving at 04/04/2025 10:40:00. 50 Economy ticket for £162 per person are available. Travel duration is 60h 10m
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Greyhound US63h 5m022:30ChicagoDowntown Coach Station13:35San DiegoSDSU Transit Center0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 01/04/2025 22:30:00 to SDSU Transit Center, San Diego (USA) arriving at 04/04/2025 13:35:00. 50 Economy ticket for £162 per person are available. Travel duration is 63h 5m
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FlixBus56h 5m006:10ChicagoDowntown Coach Station21:00Kansas CityGreyhound Bus Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 31/03/2025 06:10:00 to Greyhound Bus Station, Kansas City (USA) arriving at 31/03/2025 21:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 14h 50m
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FlixBus39h 55m022:20Kansas CityGreyhound Bus Station14:15San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Kansas City (USA) at 31/03/2025 22:20:00 to Old Town Transit Center, San Diego (USA) arriving at 02/04/2025 14:15:00. 50 Economy ticket for £97 per person are available. Travel duration is 39h 55m
Waiting Time 1h 20m -
Cheapest bus trips Wednesday
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Greyhound US60h 40m020:35Chicago95th Red Line Station09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 02/04/2025 20:35:00 to Old Town Transit Center, San Diego (USA) arriving at 05/04/2025 09:15:00. 50 Economy ticket for £138 per person are available. Travel duration is 60h 40m
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Greyhound US62h 5m020:35Chicago95th Red Line Station10:40San DiegoBalboa Park0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 02/04/2025 20:35:00 to Balboa Park, San Diego (USA) arriving at 05/04/2025 10:40:00. 50 Economy ticket for £138 per person are available. Travel duration is 62h 5m
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Greyhound US51h 35m014:10Chicago95th Red Line Station17:45San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 02/04/2025 14:10:00 to Old Town Transit Center, San Diego (USA) arriving at 04/04/2025 17:45:00. 50 Economy ticket for £141 per person are available. Travel duration is 51h 35m
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FlixBus61h 25m023:50Chicago95th Red Line Station13:15San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 02/04/2025 23:50:00 to Old Town Transit Center, San Diego (USA) arriving at 05/04/2025 13:15:00. 50 Economy ticket for £152 per person are available. Travel duration is 61h 25m
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FlixBus61h 45m023:50Chicago95th Red Line Station13:35San DiegoSDSU Transit Center0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 02/04/2025 23:50:00 to SDSU Transit Center, San Diego (USA) arriving at 05/04/2025 13:35:00. 50 Economy ticket for £152 per person are available. Travel duration is 61h 45m
Cheapest bus trips Thursday
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Greyhound US63h 35m022:00ChicagoUnion Station13:35San DiegoSDSU Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 03/04/2025 22:00:00 to SDSU Transit Center, San Diego (USA) arriving at 06/04/2025 13:35:00. 50 Economy ticket for £168 per person are available. Travel duration is 63h 35m
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Greyhound US51h 50m022:00ChicagoUnion Station01:50San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 03/04/2025 22:00:00 to Seaport Village, San Diego (USA) arriving at 06/04/2025 01:50:00. 50 Economy ticket for £169 per person are available. Travel duration is 51h 50m
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Greyhound US62h 55m022:00ChicagoUnion Station12:55San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 03/04/2025 22:00:00 to La Jolla Village, San Diego (USA) arriving at 06/04/2025 12:55:00. 50 Economy ticket for £169 per person are available. Travel duration is 62h 55m
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Greyhound US63h 15m022:00ChicagoUnion Station13:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 03/04/2025 22:00:00 to Old Town Transit Center, San Diego (USA) arriving at 06/04/2025 13:15:00. 50 Economy ticket for £171 per person are available. Travel duration is 63h 15m
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Greyhound US64h 15m022:00ChicagoUnion Station14:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 03/04/2025 22:00:00 to Old Town Transit Center, San Diego (USA) arriving at 06/04/2025 14:15:00. 50 Economy ticket for £171 per person are available. Travel duration is 64h 15m
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FlixBus56h 5m006:10ChicagoDowntown Coach Station21:00Kansas CityGreyhound Bus Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 31/03/2025 06:10:00 to Greyhound Bus Station, Kansas City (USA) arriving at 31/03/2025 21:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 14h 50m
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FlixBus39h 55m022:20Kansas CityGreyhound Bus Station14:15San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Kansas City (USA) at 31/03/2025 22:20:00 to Old Town Transit Center, San Diego (USA) arriving at 02/04/2025 14:15:00. 50 Economy ticket for £97 per person are available. Travel duration is 39h 55m
Waiting Time 1h 20m -
What is the best day and time to travel by bus between Chicago and San Diego?
All facts for Chicago to San Diego bus at a glance
Compare all coach operators like Greyhound US and FlixBus that travel daily 19 times by bus from Chicago to San Diego in one click. Book your Chicago to San Diego bus ticket starting from £102!
Cheapest Bus | £102 |
Fastest Bus | 48h 50m |
Earliest Coach | 06:10 |
Latest Coach | 22:30 |
Daily Bus Connections | 19 Ø |
Distance | 2,784.7 km |
Coach Companies | Greyhound US and FlixBus |
What are the cheapest coach tickets from Chicago to San Diego?
Every day, 19 buses from 2 coach companies leave Chicago for San Diego. Check the table below to find the cheapest prices for coach tickets for this route, starting from 28/03/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Chicago to San Diego
How to save money travelling from Chicago to San Diego
Book the ticket from Chicago to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Chicago to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Chicago to San Diego are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Chicago and San Diego
Here is a map with all coach stations in Chicago and San Diego. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Chicago to San Diego
FAQs for Chicago to San Diego bus
How much does a Chicago San Diego coach trip cost?
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Which bus companies serve the Chicago San Diego route?
Is there a direct bus between Chicago and San Diego?
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What equipment is available for the Chicago San Diego bus route?
Available seat classes which are offered on the bus route Chicago to San Diego
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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