Which bus from Santa Cruz, LI to Santiago, RM is the best?
Check the bus schedule for Santa Cruz, LI to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 44m | 05:00 | Santa Cruz, LI | Central Bus Station | 07:44 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 16/12/2025 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 16/12/2025 07:44:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 05:50 | Santa Cruz, LI | Central Bus Station | 08:34 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 16/12/2025 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 16/12/2025 08:34:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 06:50 | Santa Cruz, LI | Central Bus Station | 09:34 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 16/12/2025 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 16/12/2025 09:34:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 07:30 | Santa Cruz, LI | Central Bus Station | 10:14 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 16/12/2025 07:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 16/12/2025 10:14:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 08:00 | Santa Cruz, LI | Central Bus Station | 10:44 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 16/12/2025 08:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 16/12/2025 10:44:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 44m | 05:00 | Santa Cruz, LI | Central Bus Station | 07:44 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/12/2025 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/12/2025 07:44:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 05:50 | Santa Cruz, LI | Central Bus Station | 08:34 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/12/2025 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/12/2025 08:34:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 06:50 | Santa Cruz, LI | Central Bus Station | 09:34 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/12/2025 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/12/2025 09:34:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 07:30 | Santa Cruz, LI | Central Bus Station | 10:14 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/12/2025 07:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/12/2025 10:14:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 08:00 | Santa Cruz, LI | Central Bus Station | 10:44 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/12/2025 08:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/12/2025 10:44:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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Best Price Offer: The price for the cheapest coach from Santa Cruz, LI to Santiago, RM is £4 on 16/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Santa Cruz, LI and Santiago, RM?
Tuesday
is the busiest day, with more than 14 daily coaches from Santa Cruz, LI to Santiago, RM. Tuesday has instead the fewest connections, with only 14 daily coaches between Santa Cruz, LI and Santiago, RM.
The busiest time of the day is the Afternoon, with 12 coaches from Santa Cruz, LI to Santiago, RM, while Evening sees the fewest connections between Santa Cruz, LI and Santiago, RM, with 2 offers.
All facts for Santa Cruz, LI to Santiago, RM bus at a glance
Compare all coach operators like FlixBus that travel daily 14 times by bus from Santa Cruz, LI to Santiago, RM in one click. Book your Santa Cruz, LI to Santiago, RM bus ticket starting from £4!
| Cheapest Bus | £4 |
| Fastest Bus | 2h 44m |
| Earliest Coach | 05:00 |
| Latest Coach | 18:00 |
| Daily Bus Connections | 14 Ø |
| Distance | 146.4 km |
| Coach Companies | FlixBus |
What are the cheapest coach tickets from Santa Cruz, LI to Santiago, RM?
Every day, 14 buses from 1 coach companies leave Santa Cruz, LI for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 15/12/2025 and for the following days. Make sure get the cheapest bus ticket!
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday
15/12
Tuesday
16/12
£5
Wednesday
17/12
Thursday
18/12
£5
Friday
19/12
Saturday
20/12
£6
Sunday
21/12
£6
Monday
22/12
Tuesday
23/12
£5
Wednesday
24/12
Thursday
25/12
Friday
26/12
Saturday
27/12
Sunday
28/12
Monday
29/12
Tuesday
30/12
Wednesday
31/12
Thursday
01/01
Friday
02/01
Saturday
03/01
Sunday
04/01
£7
Monday
05/01
Tuesday
06/01
£5
Wednesday
07/01
£5
Thursday
08/01
Friday
09/01
Saturday
10/01
Sunday
11/01
The cheapest time to travel from Santa Cruz, LI to Santiago, RM
With a price starting from £4, Tuesday is the cheapest day for a coach from Santa Cruz, LI to Santiago, RM. Tuesday instead is the most expensive day with prices starting from £4.
Morning
is the cheapest day time for bus tickets from Santa Cruz, LI to Santiago, RM, with £4. Morning is the most expensive time of the day with prices starting from £4.
How to save money travelling from Santa Cruz, LI to Santiago, RM
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.
Book the ticket from Santa Cruz, LI to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Santa Cruz, LI to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santa Cruz, LI to Santiago, RM are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Santa Cruz, LI and Santiago, RM
Here is a map with all coach stations in Santa Cruz, LI and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Santa Cruz, LI to Santiago, RM
Check all information on comfort and services on the coaches from Santa Cruz, LI to Santiago, RM. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.
FAQs for Santa Cruz, LI to Santiago, RM bus
How much does a Santa Cruz, LI Santiago, RM coach trip cost?
This depends on, among other things, the day and travel time. The cheapest ticket for the Santa Cruz, LI Santiago, RM bus trip is available from £4 and takes 2h 44m. Compare offers and save money!
How much could I save by comparing buses from Santa Cruz, LI to Santiago, RM?
This connection is offered by 1 companies with ticket prices ranging from £4 to £5. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago, RM.
How many connections are available for the Santa Cruz, LI Santiago, RM route on average every day?
Each day, the bus route from Santa Cruz, LI to Santiago, RM is offered by roughly 14 busses. By using our search, you can compare bus schedules and find your ideal trip.
How long does a bus to Santiago, RM from Santa Cruz, LI take?
The quickest coach from Santa Cruz, LI to Santiago, RM is provided by FlixBus and takes 2h 44m. Coach tickets for this connection cost £4. However, keep in mind that the connection can take longer due to traffic.
What time is the first bus from Santa Cruz, LI to Santiago, RM?
The earliest bus to Santiago, RM departs from Santa Cruz, LI at 05:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
What time is the last coach from Santa Cruz, LI to Santiago, RM?
The latest bus to Santiago, RM departs from Santa Cruz, LI at 18:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
Which bus companies serve the Santa Cruz, LI Santiago, RM route?
Passengers looking to travel from Santa Cruz, LI to Santiago, RM can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.
Is there a direct bus between Santa Cruz, LI and Santiago, RM?
You can check all the direct connections between Santa Cruz, LI and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.
What can I take with me on the bus to Santiago, RM from Santa Cruz, LI?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santa Cruz, LI Santiago, RM bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.
What equipment is available for the Santa Cruz, LI Santiago, RM bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Cruz, LI to Santiago, RM on your planned travel date.
How does CheckMyBus find the best coach deals from Santa Cruz, LI to Santiago, RM?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Santa Cruz, LI and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Santa Cruz, LI to Santiago, RM?
Prices and availability for 14 trips between Santa Cruz, LI and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Santa Cruz, LI to Santiago, RM
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Santa Cruz, LI and to Santiago, RM
Here’s an overview of the most popular bus routes to Santa Cruz, LI and to Santiago, RM. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
- Bus Routes to Santiago, RM
- Angol to Santiago, RM coach
- Bus from Bariloche to Santiago, RM
- Bus Buenos Aires to Santiago, RM
- Catapilco to Santiago, RM bus
- Bus to Santiago, RM from Curacautin
- Bus to Santiago, RM from Curanilahue
- Coaches Freire to Santiago, RM
- La Serena to Santiago, RM coach
- Loncoche to Santiago, RM bus
- Los Vilos to Santiago, RM coach
- Matanzas to Santiago, RM coach
- Coach Mendoza to Santiago, RM
- Coach Nueva Imperial to Santiago, RM
- Coach Purén to Santiago, RM
- Coaches Requínoa to Santiago, RM
- Coach Salamanca, CO to Santiago, RM
- Coach Talcahuano to Santiago, RM
- Bus to Santiago, RM from Tocopilla
- Coach Tongoy, CO to Santiago, RM
- Bus from Valparaíso (CL) to Santiago, RM
Popular Airport Transfers to Santa Cruz, LI and to Santiago, RM
