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How to get from São Paulo to Santa Cruz de la Sierra

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What is the best way to travel from São Paulo to Santa Cruz de la Sierra?

Looking for a trip? Compare all the available Buses and Flights for the journey to Santa Cruz de la Sierra from São Paulo. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
39h 30m
£114
£118
2
Flight
2h 50m
£136
£346
38

What is the cheapest way to reach Santa Cruz de la Sierra from São Paulo?

You can get to Santa Cruz de la Sierra with just £114 by taking a Bus from La Preferida Bus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

today
from £119
tomorrow
from £114
Friday
from £114
Saturday
from £114
Sunday
from £119
Monday
from £114
Tuesday
from £114

    Cheapest Buses today

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £122
  • Cheapest Flights today

  • Gol Linhas Aéreas
    3h 5m
    0
    09:30
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    11:35
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £233
  • Aerolíneas Argentinas
    7h 30m
    0
    18:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £259
  • Boliviana de Aviación
    2h 50m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    20:25
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £260
  • Ethiopian Airlines
    25h 0m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £319
  • Air Canada
    13h 40m
    0
    12:30
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Air Canada
    Economy
    from £367

    Cheapest Buses tomorrow

  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • Cheapest Flights tomorrow

  • Aerolíneas Argentinas
    7h 30m
    0
    18:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £258
  • Boliviana de Aviación
    2h 50m
    0
    14:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £278
  • LATAM Brasil
    11h 20m
    0
    06:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £330
  • Gol Linhas Aéreas
    27h 10m
    0
    23:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £336
  • TAM Airlines
    9h 0m
    0
    07:50
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    TAM Airlines
    Economy
    from £435

    Cheapest Buses Friday

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Tietê Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • Cheapest Flights Friday

  • Gol Linhas Aéreas
    3h 5m
    0
    09:30
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    11:35
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £136
  • Boliviana de Aviación
    2h 50m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    20:25
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £257
  • Aerolíneas Argentinas
    10h 30m
    0
    15:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £302
  • Flybondi
    14h 25m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £346
  • LATAM Brasil
    11h 20m
    0
    06:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £368

    Cheapest Buses Saturday

  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • Cheapest Flights Saturday

  • Flybondi
    26h 5m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £266
  • Boliviana de Aviación
    2h 50m
    0
    14:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £277
  • LATAM Brasil
    7h 45m
    0
    21:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £300
  • Ethiopian Airlines
    12h 40m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £337
  • Aerolíneas Argentinas
    7h 30m
    0
    18:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £342

    Cheapest Buses Sunday

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £122
  • Cheapest Flights Sunday

  • Boliviana de Aviación
    2h 50m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    20:25
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £276
  • Flybondi
    26h 5m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £342
  • LATAM Brasil
    15h 45m
    0
    13:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £361
  • Aerolíneas Argentinas
    26h 25m
    0
    23:45
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £384
  • Ethiopian Airlines
    12h 40m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £411

    Cheapest Buses Monday

  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £114
  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Barra Funda Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £119
  • Cheapest Flights Monday

  • Aerolíneas Argentinas
    25h 5m
    0
    01:05
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £309
  • LATAM Brasil
    13h 8m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    06:43
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £457
  • LAN Perú
    13h 58m
    0
    17:45
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    06:43
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LAN Perú
    Economy
    from £457
  • Flybondi
    14h 25m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £466
  • Gol Linhas Aéreas
    11h 55m
    0
    14:15
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £495

    Cheapest Buses Tuesday

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Tietê Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • Cheapest Flights Tuesday

  • Gol Linhas Aéreas
    16h 45m
    0
    12:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £401
  • Aerolíneas Argentinas
    16h 10m
    0
    10:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £404
  • LATAM Brasil
    15h 45m
    0
    13:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £419
  • Ethiopian Airlines
    12h 40m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £451
  • TAM Airlines
    9h 0m
    0
    07:50
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    TAM Airlines
    Economy
    from £460

What are the fastest trips from São Paulo to Santa Cruz de la Sierra?

You can get to Santa Cruz de la Sierra from São Paulo in just 2h 50m with a Flight from Boliviana de Aviación. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

today
from 2h 50m
tomorrow
from 2h 50m
Friday
from 2h 50m
Saturday
from 2h 50m
Sunday
from 2h 50m
Monday
from 11h 55m
Tuesday
from 9h 0m

    Fastest Flights today

  • Boliviana de Aviación
    2h 50m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    20:25
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £260
  • Gol Linhas Aéreas
    3h 5m
    0
    09:30
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    11:35
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £233
  • Aerolíneas Argentinas
    7h 30m
    0
    18:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £259
  • Air Canada
    13h 40m
    0
    12:30
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Air Canada
    Economy
    from £367
  • Ethiopian Airlines
    25h 0m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £319
  • Fastest Buses today

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £122

    Fastest Flights tomorrow

  • Boliviana de Aviación
    2h 50m
    0
    14:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £278
  • Aerolíneas Argentinas
    7h 30m
    0
    18:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £258
  • TAM Airlines
    9h 0m
    0
    07:50
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    TAM Airlines
    Economy
    from £435
  • LATAM Brasil
    11h 20m
    0
    06:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £330
  • Gol Linhas Aéreas
    27h 10m
    0
    23:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £336
  • Fastest Buses tomorrow

  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119

    Fastest Flights Friday

  • Boliviana de Aviación
    2h 50m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    20:25
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £257
  • Gol Linhas Aéreas
    3h 5m
    0
    09:30
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    11:35
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £136
  • Aerolíneas Argentinas
    10h 30m
    0
    15:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £302
  • LATAM Brasil
    11h 20m
    0
    06:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £368
  • Flybondi
    14h 25m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £346
  • Fastest Buses Friday

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Tietê Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119

    Fastest Flights Saturday

  • Boliviana de Aviación
    2h 50m
    0
    14:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £277
  • Aerolíneas Argentinas
    7h 30m
    0
    18:40
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £342
  • LATAM Brasil
    7h 45m
    0
    21:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £300
  • Ethiopian Airlines
    12h 40m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £337
  • Flybondi
    26h 5m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £266
  • Fastest Buses Saturday

  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119

    Fastest Flights Sunday

  • Boliviana de Aviación
    2h 50m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    20:25
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Boliviana de Aviación
    Economy
    from £276
  • Ethiopian Airlines
    12h 40m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £411
  • LATAM Brasil
    15h 45m
    0
    13:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £361
  • Flybondi
    26h 5m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £342
  • Aerolíneas Argentinas
    26h 25m
    0
    23:45
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £384
  • Fastest Buses Sunday

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £122

    Fastest Flights Monday

  • Gol Linhas Aéreas
    11h 55m
    0
    14:15
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £495
  • LATAM Brasil
    13h 8m
    0
    18:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    06:43
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £457
  • LAN Perú
    13h 58m
    0
    17:45
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    06:43
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LAN Perú
    Economy
    from £457
  • Flybondi
    14h 25m
    0
    03:35
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    17:00
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Flybondi
    Economy
    from £466
  • Aerolíneas Argentinas
    25h 5m
    0
    01:05
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £309
  • Fastest Buses Monday

  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Tietê Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £114
  • La Preferida Bus
    39h 30m
    0
    13:00
    São Paulo
    Barra Funda Bus Station
    03:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    £119

    Fastest Flights Tuesday

  • TAM Airlines
    9h 0m
    0
    07:50
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    15:50
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    TAM Airlines
    Economy
    from £460
  • Ethiopian Airlines
    12h 40m
    0
    17:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Ethiopian Airlines
    Economy
    from £451
  • LATAM Brasil
    15h 45m
    0
    13:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    LATAM Brasil
    Economy
    from £419
  • Aerolíneas Argentinas
    16h 10m
    0
    10:00
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    01:10
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Aerolíneas Argentinas
    Economy
    from £404
  • Gol Linhas Aéreas
    16h 45m
    0
    12:55
    São Paulo/Guarulhos Airport
    São Paulo/Guarulhos Airport - Terminal 1
    04:40
    Viru Viru Airport
    Santa Cruz de la Sierra Airport
    0
    Gol Linhas Aéreas
    Economy
    from £401
  • Fastest Buses Tuesday

  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Tietê Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £114
  • La Preferida Bus
    39h 30m
    0
    14:00
    São Paulo
    Barra Funda Bus Station
    04:30
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    Economy
    £119
Here you will find all operators and timetables for a Bus from São Paulo to Santa Cruz de la Sierra

What are the most popular stations in São Paulo and Santa Cruz de la Sierra?

In São Paulo, you will usually depart from Tietê Bus Station, Barra Funda Bus Station or Jabaquara Coach Station, while in Santa Cruz de la Sierra you will be arriving at Terminal Bimodal, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Santa Cruz de la Sierra from São Paulo? With 7 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between São Paulo and Santa Cruz de la Sierra, you can pay as low as £114 with a Bus from La Preferida Bus.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Boliviana de Aviación: you will get to Santa Cruz de la Sierra in just 2h 50m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting São Paulo and Santa Cruz de la Sierra are La Preferida Bus, Aerolíneas Argentinas and LATAM Brasil, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in São Paulo and Santa Cruz de la Sierra is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Congonhas - São Paulo Airport or to Cotoca, and look at flights from São Paulo/Guarulhos Airport, and landing at Viru Viru Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from São Paulo to Santa Cruz de la Sierra?

The most popular companies between São Paulo and Santa Cruz de la Sierra, are La Preferida Bus, Aerolíneas Argentinas and LATAM Brasil. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: La Preferida Bus

Airlines: Aerolíneas Argentinas, LATAM Brasil, Gol Linhas Aéreas and 6 more.

All you need to know when you travel from São Paulo to Santa Cruz de la Sierra

Check all information on comfort and services on all modes of transports from São Paulo to Santa Cruz de la Sierra. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from São Paulo to Santa Cruz de la Sierra

How can I reach Santa Cruz de la Sierra from São Paulo?

Every day, there are on average 7 connections between Bus and Flight, with which you can get to Santa Cruz de la Sierra from São Paulo.

How far is Santa Cruz de la Sierra from São Paulo?

The distance between São Paulo and Santa Cruz de la Sierra is 1,835.4 km.

What is the most ecofriendly mode of transport between São Paulo and Santa Cruz de la Sierra?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 50 kgs of CO2, a train 64 kgs, a car 312 kgs, and a flight 452 kgs.

What is the cheapest mode of transport from São Paulo to Santa Cruz de la Sierra?

You can get to Santa Cruz de la Sierra with just £114 by taking a Bus from La Preferida Bus.

What is the fastest way to get from São Paulo to Santa Cruz de la Sierra?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santa Cruz de la Sierra in just 2h 50m with a Flight from Boliviana de Aviación.

More routes to São Paulo and to Santa Cruz de la Sierra

Looking for more options? Here you can see the most popular routes to São Paulo and to Santa Cruz de la Sierra. Simply click on a connection, and you’ll find all the details about the route!

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